{"id":"W4407308404","doi":"10.3390/pharmaceutics17020219","title":"3D-Printed Contact Lenses to Release Polyvinyl Alcohol as a Therapeutic Agent for the Treatment of Dry Eyes","year":2025,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"University of Waterloo; Natural Sciences and Engineering Research Council of Canada; Mitacs; Canadian Optometric Education Trust Fund; Government of Ontario","keywords":"Polyvinyl alcohol; Artificial tears; Materials science; Viscosity; Biomedical engineering; Composite material; Ophthalmology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001085787,0.000199433,0.0003327485,0.00009078845,0.00009809365,0.00001619133,0.000118805,0.00005598106,0.00009188025],"category_scores_gemma":[0.00005631636,0.0001301324,0.0002362453,0.0001901652,0.00003573707,0.00002471013,0.00002580756,0.00009141811,0.00003986896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001419729,"about_ca_system_score_gemma":0.0001939494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001528657,"about_ca_topic_score_gemma":0.0000279516,"domain_scores_codex":[0.9990078,0.00004272489,0.0002721986,0.0002207463,0.0001743394,0.0002821404],"domain_scores_gemma":[0.9989121,0.0003526998,0.00006510212,0.0004244618,0.0001392842,0.0001063744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005029955,0.002308554,0.07584608,0.0004008519,0.003996356,0.00006101348,0.00283284,0.00007510518,0.2389185,0.002326817,0.0003959542,0.667808],"study_design_scores_gemma":[0.004783645,0.001492924,0.00972447,0.0001347615,0.002013582,0.000001990095,0.0006976809,0.002089339,0.4334893,0.00006032299,0.545364,0.0001480248],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9718882,0.01279612,0.00220453,0.008754493,0.0004950161,0.002564531,0.00004302548,0.00007242374,0.00118164],"genre_scores_gemma":[0.9839436,0.003591248,0.0002883702,0.007793961,0.00007455539,0.0001492894,0.000009666178,0.00002442992,0.004124859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6676599,"threshold_uncertainty_score":0.5306644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07173197725270529,"score_gpt":0.4032895059740699,"score_spread":0.3315575287213646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}