{"id":"W4407339240","doi":"10.1016/j.jaci.2024.12.607","title":"Garadacimab Real-World Treatment Outcomes Of Effectiveness, Safety, And Quality-Of-Life In Patients With HAE (GREAT) Study Design","year":2025,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"AllerGen","funders":"","keywords":"Quality of life (healthcare); Quality (philosophy); Medicine; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005423966,0.001880246,0.002191752,0.0007551951,0.0007641226,0.001642246,0.001048685,0.001313205,0.004840878],"category_scores_gemma":[0.00543968,0.0006842581,0.0041633,0.000908691,0.001135413,0.001532273,0.001197353,0.001771337,0.0005795791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001145972,"about_ca_system_score_gemma":0.001155572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001251984,"about_ca_topic_score_gemma":0.001820193,"domain_scores_codex":[0.9953907,0.002622724,0.0004118104,0.0008130035,0.0003132232,0.0004484638],"domain_scores_gemma":[0.9960582,0.001159062,0.001607096,0.0004141194,0.000319649,0.0004418188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7527171,0.007221478,0.185055,0.002637834,0.02301772,0.0004083195,0.0004267558,0.003300484,0.002560979,0.001016489,0.002572687,0.01906514],"study_design_scores_gemma":[0.2602932,0.1767122,0.51318,0.0006453002,0.02659124,0.0007614401,0.0007414829,0.006178049,0.00254914,0.001990563,0.009940762,0.0004166538],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.9864663,0.002309723,0.001145183,0.0002276292,0.0001806855,0.003262533,0.004117448,0.00002663335,0.00226387],"genre_scores_gemma":[0.9845729,0.0004320891,0.001204254,0.0004979335,0.0002251419,0.008111598,0.003651352,0.00001184382,0.001292781],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.005423966,"threshold_uncertainty_score":0.02868497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05365354409686728,"score_gpt":0.3736477466887336,"score_spread":0.3199942025918663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}