{"id":"W4407344223","doi":"10.1177/13872877251317220","title":"Enlarged perivascular spaces correlate with blood-brain barrier leakage and cognitive impairment in Alzheimer's disease","year":2025,"lang":"en","type":"article","venue":"Journal of Alzheimer s Disease","topic":"Cerebrospinal fluid and hydrocephalus","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Verbal fluency test; Cognition; Psychology; Blood–brain barrier; Alzheimer's disease; Neuroscience; Pathology; Internal medicine; Neuropsychology; Disease; Medicine; Central nervous system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006325084,0.0005258795,0.000359113,0.001180561,0.0003218508,0.0007554023,0.0002939451,0.0003917459,0.00190092],"category_scores_gemma":[0.00203347,0.0002108881,0.0002974008,0.000653927,0.0005189765,0.0005152159,0.0006147965,0.0004361019,0.0001350695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001510111,"about_ca_system_score_gemma":0.0001693079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008511957,"about_ca_topic_score_gemma":0.0009391772,"domain_scores_codex":[0.9997718,0.0000534654,0.00003496966,0.0000495224,0.00005192181,0.00003832463],"domain_scores_gemma":[0.9981097,0.0003360056,0.001110009,0.00007614768,0.0001942535,0.0001738677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00118198,0.0001017649,0.9866819,0.0001227641,0.0001993112,0.0006327766,0.0001676521,0.000104571,0.001984039,0.00008529513,0.0001206047,0.008617457],"study_design_scores_gemma":[0.00001289433,0.0001375423,0.9970535,0.00001719034,0.0000740149,0.001692271,0.0001310011,0.0001414476,0.0003120798,0.0002680081,0.0001551202,0.00000496521],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970148,0.002269228,0.0001725014,0.00003722165,0.000008992441,0.000007848359,0.00007224185,0.000006058152,0.0004111723],"genre_scores_gemma":[0.9991787,0.0004431145,0.0001547844,0.00001207329,0.00002743345,0.000004815907,0.00006646715,0.000001285823,0.00011125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00190092,"threshold_uncertainty_score":0.00635916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01260509958133401,"score_gpt":0.262175989398897,"score_spread":0.249570889817563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}