{"id":"W4407351247","doi":"10.1128/mbio.02964-24","title":"mGem: The complexity of viral entry—one virus, many receptors","year":2025,"lang":"en","type":"review","venue":"mBio","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; University of California, San Francisco; Children's Hospital of Pittsburgh; U.S. Public Health Service; Heinz Endowments","keywords":"Capsid; Viral entry; Receptor; Virology; Internalization; Tissue tropism; Tropism; Biology; Virus; Viral replication; Viral protein; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004284671,0.0007245056,0.001028005,0.001734337,0.0003117607,0.00149797,0.0008024388,0.00114293,0.003216259],"category_scores_gemma":[0.0004527595,0.0002267219,0.0003245342,0.00142267,0.000920079,0.002072793,0.000745593,0.002293968,0.002639406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008568243,"about_ca_system_score_gemma":0.001182489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001133767,"about_ca_topic_score_gemma":0.001002,"domain_scores_codex":[0.9998211,0.00003681989,0.00001998948,0.00003272974,0.00006758155,0.00002177515],"domain_scores_gemma":[0.9998091,0.00008586011,0.00002005251,0.000009191169,0.00004958446,0.00002624551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000061942,0.00003260707,0.0001987036,0.008146072,0.00004820999,0.0002258317,0.0001234323,0.0002560102,0.002372006,0.0186251,0.04124931,0.9286607],"study_design_scores_gemma":[0.000004149572,0.00003303914,0.0003236511,0.001276521,0.00001739643,0.0006982352,0.00005010304,0.00004415455,0.0002468163,0.003414285,0.9938833,0.000008347943],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001077167,0.9968778,0.0002212883,0.0007144134,0.000305365,0.000003491677,0.00001578021,0.00001172512,0.001742496],"genre_scores_gemma":[0.0008207705,0.9971626,0.0001907649,0.00041213,0.0002895609,0.0000055043,0.00002850001,0.000002518682,0.00108768],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003216259,"threshold_uncertainty_score":0.01075947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1523227108564098,"score_gpt":0.4041174922348347,"score_spread":0.2517947813784249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}