{"id":"W4407353377","doi":"10.3390/microorganisms13020392","title":"Uncovering the Multifaceted Role of PA2649 (nuoN) in Type III Secretion System and Other Virulence Production in Pseudomonas aeruginosa PAO1","year":2025,"lang":"en","type":"article","venue":"Microorganisms","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Science Foundation of Shaanxi Province","keywords":"Virulence; Pseudomonas aeruginosa; Operon; Type three secretion system; Biology; Biofilm; Pyocyanin; Microbiology; Secretion; Gene; Regulator; Cell biology; Quorum sensing; Genetics; Mutant; Bacteria; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008601254,0.0003614441,0.0001906939,0.0001835615,0.0001155331,0.0002308483,0.000156778,0.0002667272,0.000479253],"category_scores_gemma":[0.0001066291,0.0001117757,0.0003400753,0.0001378526,0.0001759991,0.0002103491,0.0002862847,0.0003762982,0.0004057987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001796062,"about_ca_system_score_gemma":0.0001500258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000547227,"about_ca_topic_score_gemma":0.0004869844,"domain_scores_codex":[0.9999256,0.00001184005,0.000006828045,0.00001728437,0.00002431263,0.00001409197],"domain_scores_gemma":[0.9999243,0.00001059529,0.00002854489,0.00001032364,0.000008090079,0.00001820056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002203594,0.000007477058,0.000311258,0.000008036751,0.000001015203,0.00004675868,0.000005450617,0.00002921254,0.9991171,0.0000272026,0.000006806166,0.0004176504],"study_design_scores_gemma":[0.000006724792,0.0002369219,0.02626726,0.000007723303,0.00001263817,0.000783934,0.00007247436,0.002586788,0.9677614,0.0001407434,0.002112057,0.00001129224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940413,0.0005254857,0.004289387,0.0001249101,0.000009100992,0.0000155518,0.000399256,0.00007962847,0.0005153588],"genre_scores_gemma":[0.9933214,0.0003922597,0.004050859,0.00006135616,0.000006899244,0.00001949856,0.0007230467,0.00002624449,0.001398424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000547227,"threshold_uncertainty_score":0.001603246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004013695077349202,"score_gpt":0.2157550930309675,"score_spread":0.2117413979536183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}