{"id":"W4407374986","doi":"10.1002/adtp.202400347","title":"Photothermal Therapy: From Encouraging Lab Results to Lackluster Clinical Translation","year":2025,"lang":"en","type":"article","venue":"Advanced Therapeutics","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canada First Research Excellence Fund","keywords":"Photothermal therapy; Translation (biology); Psychology; Medicine; Nanotechnology; Materials science; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005870754,0.00081422,0.0006362843,0.000512497,0.000377508,0.003366481,0.0009260494,0.001820298,0.01015208],"category_scores_gemma":[0.005318149,0.00023217,0.0007368831,0.0005398032,0.001434886,0.001855787,0.001207679,0.00282528,0.003787545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008640779,"about_ca_system_score_gemma":0.001838974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005154302,"about_ca_topic_score_gemma":0.0006351465,"domain_scores_codex":[0.998476,0.0004995789,0.0001126189,0.0002150528,0.0005504841,0.0001463107],"domain_scores_gemma":[0.9959134,0.001608975,0.0004402233,0.000466925,0.001176188,0.0003942871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001218291,0.002697414,0.002049733,0.004562482,0.000246103,0.0006367169,0.0005150482,0.002310677,0.1314662,0.02023614,0.06257226,0.771489],"study_design_scores_gemma":[0.0005524361,0.01244632,0.00576837,0.003802706,0.0002994214,0.001551005,0.0008256329,0.003117885,0.1975134,0.02208618,0.7518905,0.000146165],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.09972794,0.6656181,0.07390843,0.07874893,0.007734537,0.001513625,0.002060656,0.001466247,0.06922162],"genre_scores_gemma":[0.4597554,0.4240091,0.04643833,0.0330915,0.004007119,0.001636536,0.00237772,0.0006353563,0.02804895],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01015208,"threshold_uncertainty_score":0.03396207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03898889978500074,"score_gpt":0.3217046340513277,"score_spread":0.282715734266327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}