{"id":"W4407374986","doi":"10.1002/adtp.202400347","title":"Photothermal Therapy: From Encouraging Lab Results to Lackluster Clinical Translation","year":2025,"lang":"en","type":"article","venue":"Advanced Therapeutics","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canada First Research Excellence Fund","keywords":"Photothermal therapy; Translation (biology); Psychology; Medicine; Nanotechnology; Materials science; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002065581,0.0002699003,0.0003048867,0.0001120759,0.00007053628,0.00004754302,0.0002872441,0.0001693239,0.00002773523],"category_scores_gemma":[0.00001342706,0.0002593221,0.0001067677,0.0004088928,0.00004063151,0.0002078619,0.00001974216,0.0003145873,0.00005004939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009644843,"about_ca_system_score_gemma":0.0000399983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000010128,"about_ca_topic_score_gemma":0.00004234223,"domain_scores_codex":[0.9985012,0.00003424771,0.0006016204,0.0003144922,0.0001849136,0.0003634716],"domain_scores_gemma":[0.9989383,0.0003711688,0.00005065943,0.0004959962,0.00006344851,0.00008044642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000752437,0.0000470076,0.0003577345,0.00001277062,0.000304775,0.000003661693,0.000990584,0.01890776,0.1300223,0.00007359499,0.0001386299,0.8483887],"study_design_scores_gemma":[0.006371003,0.0001573696,0.002229191,0.0001582436,0.00007760109,7.587559e-7,0.0001641496,0.01757365,0.132373,0.003757345,0.8365155,0.0006221373],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7690541,0.009048427,0.1940543,0.001214325,0.005557078,0.001487978,0.0004265696,0.001547312,0.01760993],"genre_scores_gemma":[0.9813959,0.002176949,0.01201637,0.003574125,0.0002156445,0.00004061642,0.00005777361,0.00009837242,0.000424255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8477666,"threshold_uncertainty_score":0.9999859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03898889978500074,"score_gpt":0.3217046340513277,"score_spread":0.282715734266327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}