{"id":"W4407408699","doi":"10.51731/cjht.2025.1073","title":"Zilucoplan (Zilbrysq)","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Computer science","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002028484,0.0003558419,0.0004675546,0.0006079209,0.0001948644,0.0004761565,0.0004853468,0.0005588458,0.02735086],"category_scores_gemma":[0.0003614308,0.0001531497,0.0003769193,0.000347643,0.0001319068,0.0003153413,0.0004373133,0.001608537,0.0127768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004730066,"about_ca_system_score_gemma":0.0003847697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002029467,"about_ca_topic_score_gemma":0.003264903,"domain_scores_codex":[0.9998331,0.00002826637,0.00001154058,0.0000313682,0.0000600007,0.00003572461],"domain_scores_gemma":[0.9999229,0.000009968401,0.00001640895,0.00000697736,0.00001626277,0.00002750357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002987824,0.0007714365,0.001566429,0.001861695,0.0001862503,0.000916561,0.00006801997,0.0005082836,0.04214845,0.003046553,0.1350011,0.8109374],"study_design_scores_gemma":[0.00799194,0.004282518,0.0123308,0.0005428585,0.000193363,0.006507577,0.0000560977,0.001226805,0.01863817,0.001215515,0.9469708,0.00004350138],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.2146467,0.2663848,0.01780344,0.01363307,0.003028087,0.003525523,0.02102961,0.01112549,0.4488234],"genre_scores_gemma":[0.6859121,0.06509706,0.01265485,0.01001851,0.0006059612,0.001103809,0.02439274,0.0003873583,0.1998275],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.02735086,"threshold_uncertainty_score":0.09149778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007438099556752454,"score_gpt":0.2584332955643642,"score_spread":0.2509951960076117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}