{"id":"W4407416005","doi":"10.1007/s11912-025-01648-4","title":"Cell-free Tumor DNA: a Promising Technology for Diagnosis, Surveillance and Therapeutic Decision in Urothelial Carcinoma of the Bladder","year":2025,"lang":"en","type":"review","venue":"Current Oncology Reports","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"NOSM University; Université Laval","funders":"","keywords":"Medicine; Urothelial carcinoma; Oncology; Cell-free fetal DNA; Cancer research; Internal medicine; Bladder cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004502789,0.00044482,0.00231841,0.0004124536,0.0000805759,0.000008798149,0.0002515119,0.0004527646,0.00001338237],"category_scores_gemma":[0.0006025354,0.0002808333,0.0004227729,0.000573203,0.0002602958,0.0000177289,0.00027611,0.0005104069,5.949084e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003723043,"about_ca_system_score_gemma":0.003144389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001820266,"about_ca_topic_score_gemma":0.00005758533,"domain_scores_codex":[0.9972981,0.0001648873,0.001201708,0.0007506235,0.0002139268,0.0003707729],"domain_scores_gemma":[0.9971877,0.0006970601,0.0008875943,0.001012978,0.0001460725,0.00006859584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007411042,0.0006818912,0.06219633,0.01243419,0.0001391161,0.0001833904,0.00004835063,1.012702e-7,0.000002212238,0.0000173572,0.00128475,0.9229382],"study_design_scores_gemma":[0.002869598,0.0006858474,0.004306672,0.014894,0.001829583,0.001232876,0.0000174741,0.000001748894,0.00009742517,0.001154126,0.972667,0.0002436098],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006017486,0.9859198,0.00002012061,0.0002041441,0.001903633,0.005536735,0.00009454974,0.00002803869,0.0002755279],"genre_scores_gemma":[0.01177841,0.9848654,0.0001640348,0.00005506565,0.0001592135,0.002758833,0.00002876442,0.00005309974,0.0001371385],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9713823,"threshold_uncertainty_score":0.9999644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04809905546353031,"score_gpt":0.3868624913836161,"score_spread":0.3387634359200858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}