{"id":"W4407439191","doi":"10.1055/s-0044-1801671","title":"Caplacizumab Added to Plasma Exchange and Immunosuppression Accelerates Recovery and Improves Survival in Immune-Mediated TTP: an International Real-World Study of the IWG-TTP (The Capla 1000+Project)","year":2025,"lang":"en","type":"article","venue":"Hämostaseologie","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; University Health Network","funders":"","keywords":"Immunosuppression; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003130047,0.000951915,0.00133015,0.0004255699,0.0003792175,0.001483399,0.0005932392,0.001304579,0.001717425],"category_scores_gemma":[0.002264719,0.0002457282,0.001288967,0.0006204143,0.0009367891,0.0007255417,0.0004305103,0.001987345,0.0003842342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007948527,"about_ca_system_score_gemma":0.0008178716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001264408,"about_ca_topic_score_gemma":0.0005329301,"domain_scores_codex":[0.9988396,0.0006651951,0.00005594609,0.0001587022,0.0001078401,0.0001727213],"domain_scores_gemma":[0.9985445,0.0003587422,0.0003153697,0.0002052365,0.0001175068,0.000458826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7155226,0.04532072,0.03755133,0.0006959281,0.002297577,0.0005657424,0.0002689848,0.001539351,0.0173716,0.0002181539,0.003584419,0.1750635],"study_design_scores_gemma":[0.1304957,0.6046254,0.2425473,0.0002355413,0.003314448,0.00166406,0.0004730585,0.003210167,0.007178384,0.000262523,0.005852771,0.0001406127],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996792,0.00191407,0.0001944879,0.0002023937,0.00007055126,0.0001052208,0.0002822408,0.0000191274,0.0004198166],"genre_scores_gemma":[0.996897,0.00108785,0.0004189126,0.0002172244,0.0001748276,0.0001175097,0.0007830999,0.00001007934,0.0002935508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003130047,"threshold_uncertainty_score":0.01655346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03287893490177565,"score_gpt":0.3171757771611737,"score_spread":0.284296842259398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}