{"id":"W4407502351","doi":"10.1016/j.bpj.2024.11.1659","title":"BPS2025 - Cryo-EM investigation of ryanodine receptor type 3","year":2025,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Electron Spin Resonance Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Ryanodine receptor; Biophysics; Chemistry; Receptor; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007893657,0.0000881988,0.0001328681,0.00003827807,0.00006824583,0.00001323099,0.0001304182,0.00006595004,0.0000128092],"category_scores_gemma":[0.00009711167,0.00007501548,0.00007690079,0.0001846815,0.00009475683,0.000002942689,0.00006741058,0.0001188117,0.000008655089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001612699,"about_ca_system_score_gemma":0.0001157964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000191117,"about_ca_topic_score_gemma":0.000001767029,"domain_scores_codex":[0.9994038,0.00003762635,0.0001783246,0.0001312733,0.000105734,0.0001432107],"domain_scores_gemma":[0.999545,0.000008674368,0.000088184,0.0001225664,0.0001931031,0.00004248219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007630289,0.00002567417,0.001695428,0.00001115229,0.00006772178,4.851251e-7,0.00001666739,0.000002824262,0.9802383,0.00044883,0.01518705,0.00222953],"study_design_scores_gemma":[0.000300758,0.0003464814,0.01202541,0.00003709854,0.00001882831,0.000003092773,0.00003340079,0.00001025859,0.9675135,0.0002838224,0.01934618,0.00008116496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975849,0.0006280416,0.0003504438,0.0005365341,0.000257103,0.00005087509,0.000003707464,0.000004991419,0.0005834346],"genre_scores_gemma":[0.9970506,0.000443578,0.0007287785,0.0002357548,0.000370936,0.000002534278,0.00001147004,0.000006931662,0.001149403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01272483,"threshold_uncertainty_score":0.3059043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00850587187357484,"score_gpt":0.2656938962095425,"score_spread":0.2571880243359677,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}