{"id":"W4407570874","doi":"10.1111/ejh.14392","title":"Sustained Improvement in Health‐Related Quality of Life in Transplant‐Ineligible Newly Diagnosed Multiple Myeloma Treated With Daratumumab, Lenalidomide, and Dexamethasone: <scp>MAIA</scp> Final Analysis of Patient‐Reported Outcomes","year":2025,"lang":"en","type":"article","venue":"European Journal Of Haematology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; University of Calgary","funders":"Janssen Research and Development; Johnson and Johnson; Janssen Scientific Affairs; National Cancer Institute; Kite Pharma; Celgene; Amgen","keywords":"Daratumumab; Lenalidomide; Medicine; Dexamethasone; Multiple myeloma; Internal medicine; Oncology; Quality of life (healthcare)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005617836,0.0004538322,0.001570988,0.000353756,0.0002169317,0.0008384227,0.0005004603,0.000328444,0.001099424],"category_scores_gemma":[0.002962282,0.000183666,0.002875477,0.0003489346,0.0003036787,0.0004321632,0.0004850798,0.0009037167,0.00008798017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006030112,"about_ca_system_score_gemma":0.0008049265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000812844,"about_ca_topic_score_gemma":0.00174295,"domain_scores_codex":[0.998135,0.001116541,0.0001293159,0.0002143148,0.0002179863,0.0001867986],"domain_scores_gemma":[0.9973641,0.001151489,0.0008799192,0.0001425589,0.000135878,0.0003259833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5191486,0.003389444,0.4071642,0.0005873045,0.0133249,0.0001304888,0.0002025951,0.003890429,0.006171567,0.0001039862,0.0008663618,0.04502022],"study_design_scores_gemma":[0.02632522,0.1344706,0.8208775,0.00007044663,0.007639803,0.0002603141,0.0001682459,0.005658905,0.003455945,0.0001511337,0.0008827131,0.0000391181],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988728,0.0004842434,0.0001094215,0.00003853881,0.00000985303,0.000052563,0.0002829492,0.000006232508,0.0001434243],"genre_scores_gemma":[0.999324,0.00006017197,0.0001107356,0.00003030561,0.00001103403,0.00005696615,0.0003339919,0.000001524364,0.00007137685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005617836,"threshold_uncertainty_score":0.02971035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03077110743143454,"score_gpt":0.3157290462354384,"score_spread":0.2849579388040039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}