{"id":"W4407603264","doi":"10.1093/bioadv/vbag179","title":"CycleMix: Gaussian Mixture Modeling of the Cell Cycle","year":2025,"lang":"en","type":"preprint","venue":"Bioinformatics Advances","topic":"Gene Regulatory Network Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Gaussian; Mixture model; Computer science; Statistical physics; Artificial intelligence; Physics; Chemistry; Computational chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001566891,0.001276543,0.0009421993,0.0008264242,0.0005545021,0.001270889,0.001976841,0.001300622,0.005924657],"category_scores_gemma":[0.002992301,0.0007051781,0.001626914,0.001022043,0.0006298069,0.0009120335,0.001117982,0.001962507,0.00362574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001103044,"about_ca_system_score_gemma":0.001486623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01010727,"about_ca_topic_score_gemma":0.01234452,"domain_scores_codex":[0.9995597,0.0001076379,0.00001456355,0.0001868813,0.00008740766,0.00004375305],"domain_scores_gemma":[0.9992948,0.0003936396,0.00004938118,0.0001015838,0.0001235973,0.00003692848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0005631332,0.0001560311,0.005800952,0.000390236,0.000368974,0.0001193267,0.0002287355,0.6322014,0.01792273,0.03251804,0.03578831,0.2739421],"study_design_scores_gemma":[0.00001425426,0.00001354051,0.0006497441,0.000009762078,0.00001225842,0.00002185091,0.000007613713,0.980521,0.002157648,0.01066256,0.005909925,0.00001983484],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.01096682,0.0007584018,0.9768439,0.0002886287,0.000127275,0.0001253563,0.003223746,0.006644403,0.001021469],"genre_scores_gemma":[0.2855701,0.001462975,0.6624204,0.0007709383,0.0003943159,0.001770363,0.0231433,0.004072913,0.02039471],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.01010727,"threshold_uncertainty_score":0.0200969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005661072395691977,"score_gpt":0.2324187109483499,"score_spread":0.226757638552658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}