{"id":"W4407640482","doi":"10.1099/acmi.0.000925.v3","title":"Immunogenicity of virus-like particle vaccine candidates against SARS-CoV-2 infection","year":2025,"lang":"en","type":"article","venue":"Access Microbiology","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute on Deafness and Other Communication Disorders; Canadian Institutes of Health Research","keywords":"Immunogenicity; Virology; Virus; Vaccination; Antibody; Virus-like particle; Neutralizing antibody; Biology; Immunity; Immune system; Immunology; Gene; Recombinant DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002588681,0.0003625425,0.0002747605,0.0002003322,0.0000967729,0.000288066,0.0001765927,0.000429618,0.001047763],"category_scores_gemma":[0.0002690425,0.00010286,0.0002477003,0.0001021681,0.0001142124,0.0002595685,0.0001757657,0.0004607959,0.0002936093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001785256,"about_ca_system_score_gemma":0.0001316657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001776879,"about_ca_topic_score_gemma":0.0001748743,"domain_scores_codex":[0.9998763,0.00002818462,0.000009613508,0.00001756836,0.00003258259,0.00003579097],"domain_scores_gemma":[0.999922,0.00001510791,0.00001810839,0.000006460362,0.00001666285,0.00002158679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003748068,0.0002252803,0.0006387005,0.000052625,0.00001606977,0.00005838493,0.00002294963,0.0004606795,0.9950935,0.00008569736,0.00008292231,0.002888449],"study_design_scores_gemma":[0.0002388438,0.01430969,0.01208548,0.00003427117,0.00008215113,0.0006060308,0.00008703218,0.003575251,0.9643357,0.0001557217,0.004472833,0.00001696853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979653,0.0004828623,0.0008708118,0.00004531066,0.00002940242,0.00003781979,0.00006976733,0.00001394626,0.0004847907],"genre_scores_gemma":[0.9972559,0.0003105919,0.001015567,0.00006614889,0.00001756081,0.0000375277,0.0004870735,0.000006188733,0.0008034194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001047763,"threshold_uncertainty_score":0.003505111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03236156713621019,"score_gpt":0.3691711603813096,"score_spread":0.3368095932450994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}