{"id":"W4407683020","doi":"10.1021/acs.oprd.4c00422","title":"Inverse Transformation of Glycine by Crystal Size Control","year":2025,"lang":"en","type":"article","venue":"Organic Process Research & Development","topic":"Crystallization and Solubility Studies","field":"Materials Science","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Process Research Ortech (Canada)","funders":"National Research Foundation of Korea","keywords":"Glycine; Transformation (genetics); Inverse; Crystal (programming language); Chemistry; Mathematics; Materials science; Computer science; Amino acid; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001427918,0.0001074967,0.0002171181,0.000119506,0.0002969377,0.00005188739,0.0002859037,0.00005602763,0.001502051],"category_scores_gemma":[0.0009575428,0.00009375303,0.00001995582,0.0006989587,0.000182675,0.0001900658,0.0000746519,0.0001195142,0.00004864053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001890409,"about_ca_system_score_gemma":0.0008217682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001616696,"about_ca_topic_score_gemma":0.00009716851,"domain_scores_codex":[0.998165,0.0001126455,0.0004353508,0.0002454018,0.0007030946,0.0003385008],"domain_scores_gemma":[0.9987609,0.0001951785,0.00005587056,0.0001518271,0.0007668279,0.0000693902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001483279,0.0002510669,0.0005473745,0.0005763943,0.00003192124,7.711594e-7,0.006836486,0.00001065227,0.9858373,0.000456578,0.004116186,0.001186942],"study_design_scores_gemma":[0.001773004,0.00007735835,0.001874298,0.0001205772,0.000008420386,8.514833e-7,0.00371529,0.0001472259,0.9675768,0.00098165,0.02356255,0.0001619504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749154,0.0002710221,0.01651826,0.002470841,0.0001090405,0.0007597292,0.00002672718,0.00008198217,0.004847011],"genre_scores_gemma":[0.9975984,0.00007424352,0.0002979697,0.0001208642,0.000006894791,0.00006862565,0.00001034513,0.000007471322,0.001815181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02268302,"threshold_uncertainty_score":0.9994107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02038081372289433,"score_gpt":0.3290364258126862,"score_spread":0.3086556120897919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}