{"id":"W4407685086","doi":"10.1053/j.gastro.2025.01.246","title":"Psychological Stress-Induced Local Immune Response to Food Antigens Increases Pain Signaling Across the Gut in Mice","year":2025,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Kingston General Hospital; Queen's University","funders":"Canadian Institutes of Health Research; China Scholarship Council; KU Leuven; Fonds Wetenschappelijk Onderzoek","keywords":"Immune system; Psychological stress; Immunology; Antigen; Fight-or-flight response; Medicine; Psychology; Biology; Clinical psychology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002942639,0.0009227924,0.0004749511,0.0008979971,0.0004079439,0.0006476649,0.0003730906,0.0009242768,0.003643499],"category_scores_gemma":[0.0002420124,0.0004948263,0.0008819927,0.0003313427,0.001211532,0.0006625269,0.0004313206,0.003085629,0.0005873414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005109191,"about_ca_system_score_gemma":0.0004346852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006254358,"about_ca_topic_score_gemma":0.001485019,"domain_scores_codex":[0.9995511,0.00006157479,0.00003329678,0.0001246745,0.00008344729,0.0001459167],"domain_scores_gemma":[0.9995748,0.00002572671,0.0001435137,0.00004201427,0.00002042658,0.0001935848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003273502,0.0006421827,0.00077231,0.0000964075,0.00002462311,0.0001350098,0.00007383492,0.0001431066,0.9924231,0.0002006272,0.0001892263,0.002026004],"study_design_scores_gemma":[0.0009945476,0.01415346,0.06094687,0.0001198718,0.0002585028,0.0008263076,0.001210599,0.003212905,0.9129291,0.000995959,0.004265304,0.00008661095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995604,0.000721103,0.001300713,0.000447941,0.0001339292,0.00004344115,0.0007445653,0.00008607363,0.0009182426],"genre_scores_gemma":[0.990573,0.001144796,0.00196739,0.0006053024,0.00008220685,0.000215587,0.0007730973,0.00006933486,0.004569374],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003643499,"threshold_uncertainty_score":0.01218879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02305625698777859,"score_gpt":0.3133237255079074,"score_spread":0.2902674685201288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}