{"id":"W4407748997","doi":"10.1161/jaha.124.037899","title":"In‐Hospital or Out‐of‐Hospital Initiation of Sacubitril/Valsartan Versus Valsartan in Patients With Mildly Reduced or Preserved Ejection Fraction After A Worsening Heart Failure Event: The PARAGLIDE‐HF Trial","year":2025,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"Heart Failure Treatment and Management","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Université de Sherbrooke","funders":"","keywords":"Medicine; Ejection fraction; Valsartan; Sacubitril; Heart failure; Tolerability; Sacubitril, Valsartan; Cardiology; Internal medicine; Natriuretic peptide; Hyperkalemia; Renal function; Clinical endpoint; Randomized controlled trial; Adverse effect; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001701102,0.001094309,0.002213757,0.000214445,0.0002077252,0.0007939795,0.0004741988,0.0007808428,0.002732292],"category_scores_gemma":[0.00155154,0.0003298972,0.00157329,0.0002313968,0.0005750955,0.0006189201,0.0002378704,0.002195793,0.0002854404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003642256,"about_ca_system_score_gemma":0.0006131972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004982466,"about_ca_topic_score_gemma":0.001992891,"domain_scores_codex":[0.9992294,0.0004748521,0.00005482096,0.0001036957,0.0000448762,0.00009234575],"domain_scores_gemma":[0.9988487,0.0003947357,0.0002706677,0.00007948658,0.00005737896,0.0003490732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9840969,0.002190425,0.00114864,0.0003512214,0.0009687141,0.00002254404,0.00003257868,0.0002249219,0.001624491,0.00006145424,0.0002656782,0.009012481],"study_design_scores_gemma":[0.9060158,0.08373699,0.006590992,0.00005006185,0.001374261,0.00005167074,0.00004107229,0.0008045549,0.0007432523,0.0001766693,0.0003959639,0.00001871185],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942859,0.003246387,0.000242621,0.0002410008,0.0002212765,0.0003853165,0.0003137301,0.00003291501,0.001030828],"genre_scores_gemma":[0.9964055,0.001159457,0.0004116545,0.0002802115,0.0003075992,0.0003639003,0.0003463516,0.000007991987,0.0007173177],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002732292,"threshold_uncertainty_score":0.009140372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01161004914793723,"score_gpt":0.2943760537839898,"score_spread":0.2827660046360526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}