{"id":"W4407768304","doi":"10.1001/jama.2025.0088","title":"Can We Omit Surgery for Low-Risk Ductal Carcinoma In Situ of the Breast?","year":2025,"lang":"en","type":"letter","venue":"JAMA","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Hamilton Health Sciences","funders":"","keywords":"Medicine; Ductal carcinoma; In situ; Carcinoma in situ; Breast surgery; Carcinoma; Breast cancer; General surgery; Oncology; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004307448,0.0003679979,0.001124165,0.0008688109,0.002671405,0.001878537,0.001765938,0.03273389,0.009810308],"category_scores_gemma":[0.02807526,0.0005492066,0.0008853328,0.001112061,0.002457585,0.002706954,0.001115758,0.01966744,0.004162177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002164613,"about_ca_system_score_gemma":0.005629318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0125441,"about_ca_topic_score_gemma":0.02682741,"domain_scores_codex":[0.9977601,0.000701483,0.0003138634,0.000196857,0.0006215355,0.0004061191],"domain_scores_gemma":[0.9869224,0.00799215,0.0007539996,0.0005087485,0.001090889,0.002731796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006703439,0.0002285172,0.01409942,0.0001770579,0.0001002647,0.001925051,0.0001333708,0.0001341082,0.0004195257,0.005610607,0.9452568,0.03124481],"study_design_scores_gemma":[0.00127698,0.0004769517,0.03206849,0.001059091,0.0003303498,0.003913553,0.001275779,0.000674507,0.0008130546,0.02945512,0.9284752,0.0001809494],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001681485,0.001765838,0.00005850923,0.982859,0.0095834,0.00001043179,0.0001496211,0.00001636941,0.003875365],"genre_scores_gemma":[0.009757716,0.001699817,0.000130543,0.9570812,0.02785659,0.00002549604,0.00007396031,0.00001072737,0.00336397],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03273389,"threshold_uncertainty_score":0.03281873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007466399484501793,"score_gpt":0.2177601061160383,"score_spread":0.2102937066315365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}