{"id":"W4407787676","doi":"10.2337/dc24-1533","title":"Comparative Efficacy of Glucagon-Like Peptide 1 Receptor Agonists for Cardiovascular Outcomes in Asian Versus White Populations: Systematic Review and Meta-analysis of Randomized Trials of Populations With or Without Type 2 Diabetes and/or Overweight or Obesity","year":2025,"lang":"en","type":"review","venue":"Diabetes Care","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; McMaster University; Population Health Research Institute","funders":"Esperion Therapeutics; Novo Nordisk; University of Glasgow; British Heart Foundation; Sanofi; Kowa Company; Alnylam Pharmaceuticals; Glenmark Pharmaceuticals; Eli Lilly and Company; AstraZeneca; CSL Behring; McMaster University; National Institute of Diabetes and Digestive and Kidney Diseases; Amgen; Pfizer; Abbott Laboratories","keywords":"Medicine; Meta-analysis; Type 2 diabetes; Internal medicine; Randomized controlled trial; Diabetes mellitus; Glucagon-like peptide-1; Endocrinology; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.002328796,0.0007487867,0.04074251,0.001041832,0.00006079263,0.00002684061,0.0001853302,0.0001880032,0.00007305195],"category_scores_gemma":[0.004299672,0.0003576573,0.006246238,0.001747626,0.0001734979,0.00009494458,0.00009613203,0.0001220847,8.700358e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001249465,"about_ca_system_score_gemma":0.0002524553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002193622,"about_ca_topic_score_gemma":0.0002132725,"domain_scores_codex":[0.9935359,0.001791502,0.003238125,0.0006264552,0.0005067057,0.000301365],"domain_scores_gemma":[0.9914605,0.004362156,0.002459743,0.00101753,0.0005953787,0.0001046606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001868575,0.0001957698,0.003609306,0.5935757,0.3995455,8.480233e-7,0.0002903374,0.000007556288,4.588048e-8,0.00004449267,0.00005978237,0.0008020736],"study_design_scores_gemma":[0.02292333,0.0005128924,0.0003197335,0.0698788,0.9048117,1.108625e-7,0.0002817553,0.00001368721,0.000002599914,0.000003048319,0.0009461449,0.000306144],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001155311,0.9757625,0.00001039182,0.00003303065,0.0001162536,0.0214374,0.001418634,0.00002155629,0.0000449134],"genre_scores_gemma":[0.004547608,0.9804509,0.004742885,0.00004568377,0.000018684,0.004842346,0.004204358,0.000064969,0.001082618],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5236969,"threshold_uncertainty_score":0.9998875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1623947790216077,"score_gpt":0.4044006538959343,"score_spread":0.2420058748743266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}