{"id":"W4407798122","doi":"10.3389/fgene.2025.1502921","title":"Comprehensive systematic review and meta-analysis of the TGF-β1 T869C gene polymorphism and autoimmune disease susceptibility","year":2025,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"Salivary Gland Disorders and Functions","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Anhui University of Chinese Medicine; Anhui University; National Natural Science Foundation of China","keywords":"Meta-analysis; Genetics; Disease; Gene; Transforming growth factor; Polymorphism (computer science); Gene polymorphism; Biology; Medicine; Immunology; Computational biology; Bioinformatics; Genotype; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002771183,0.0004087959,0.007179203,0.0003870284,0.00007084802,0.00001395168,0.0001976884,0.0001664714,0.00004812644],"category_scores_gemma":[0.0002305309,0.0002326427,0.001705544,0.001246713,0.0002276571,0.00001411726,0.0001868104,0.0002467052,5.205228e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005150328,"about_ca_system_score_gemma":0.0002676591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002796245,"about_ca_topic_score_gemma":0.000008134226,"domain_scores_codex":[0.9974198,0.0004934579,0.001166373,0.0004799961,0.0002506911,0.0001896675],"domain_scores_gemma":[0.9978085,0.0001817301,0.0004725542,0.00129876,0.0001158736,0.0001225484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.000008350354,0.00009239173,0.00118588,0.9246284,0.07094058,0.000005521601,0.00003718594,0.0000038798,8.329459e-8,0.000009232177,0.001389017,0.001699439],"study_design_scores_gemma":[0.0002048161,0.00002667457,0.001742986,0.02057676,0.9642258,0.000006739522,0.00004774751,0.00007541038,6.166589e-8,0.00004552585,0.01285288,0.0001946535],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000126933,0.9953345,0.0002618691,0.0002392246,0.0002041744,0.00345297,0.00043515,0.00001077069,0.00004864438],"genre_scores_gemma":[0.00003985044,0.9972814,0.0008186426,0.0005141959,0.000009611854,0.0002009452,0.000156024,0.00002023218,0.0009590483],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9040517,"threshold_uncertainty_score":0.9486896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04909009902439628,"score_gpt":0.3161838132873565,"score_spread":0.2670937142629602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}