{"id":"W4407809194","doi":"10.1021/acsami.4c21700","title":"In Vitro and In Vivo Radiotoxicity and Biodistribution of Thallium-201 Delivered to Cancer Cells by Prussian Blue Nanoparticles","year":2025,"lang":"en","type":"article","venue":"ACS Applied Materials & Interfaces","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Oxford Instruments (Canada)","funders":"Centre For Medical Engineering, King’s College London; Engineering and Physical Sciences Research Council; National Institute for Health and Care Research; National Institute for Health Research Health Protection Research Unit; UK Research and Innovation; Medical Research Council; University of Warwick; Wellcome Trust","keywords":"Biodistribution; In vivo; Thallium; Spect imaging; Biophysics; Prussian blue; In vitro; Materials science; Radiochemistry; Chemistry; Nuclear medicine; Biochemistry; Medicine; Biology; Electrode","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002312038,0.0003731384,0.0002113152,0.0002022845,0.0001114447,0.0002097542,0.0001782597,0.0003014265,0.0004758718],"category_scores_gemma":[0.0001629659,0.00019396,0.0001722298,0.0001445526,0.0001777006,0.0001650296,0.0001014012,0.0002239598,0.0001833475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003657675,"about_ca_system_score_gemma":0.0002719479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002589024,"about_ca_topic_score_gemma":0.001639659,"domain_scores_codex":[0.9998771,0.00002779276,0.00001109458,0.00002528972,0.0000334484,0.00002527058],"domain_scores_gemma":[0.9999069,0.00003230749,0.00002327926,0.000009164776,0.00001891101,0.000009464222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007880638,0.0000168518,0.00009581124,0.00002708376,0.000003334908,0.00002958525,0.00001949262,0.0001804185,0.9988253,0.0000237628,0.00001528103,0.0006843093],"study_design_scores_gemma":[0.000006181802,0.0004650521,0.001818284,0.000002000038,0.00001264138,0.00008441907,0.00001429241,0.001205444,0.9960659,0.000008589142,0.0003135038,0.000003761253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945202,0.001456686,0.002875776,0.00004005228,0.000009770042,0.00002468966,0.000105106,0.00005264637,0.0009151857],"genre_scores_gemma":[0.9924172,0.001266749,0.00309984,0.00003160011,0.000005731934,0.00004520058,0.0002435013,0.00002973009,0.002860494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002589024,"threshold_uncertainty_score":0.005147934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009440664042556553,"score_gpt":0.292714781987383,"score_spread":0.2832741179448264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}