{"id":"W4407837832","doi":"10.1093/ibd/izaf017","title":"Single-Cell Transcriptomic Profile of Innate Cell Populations in Mesenteric Lymph Nodes of Inflammatory Bowel Disease Patients","year":2025,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; McGill University Health Centre; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Institut de recherche, Centre universitaire de santé McGill","keywords":"Innate lymphoid cell; Innate immune system; Immune system; Immunology; Mesenteric lymph nodes; Cytotoxic T cell; Inflammatory bowel disease; Flow cytometry; Inflammation; Biology; Medicine; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001253385,0.0002077137,0.0003572638,0.0004722083,0.0001702661,0.0004229594,0.0001437955,0.0002914311,0.001399245],"category_scores_gemma":[0.000300291,0.00009575754,0.0001845393,0.0003968966,0.000158891,0.0001781558,0.0002938064,0.0002158245,0.0002646556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001481902,"about_ca_system_score_gemma":0.00006444381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003389161,"about_ca_topic_score_gemma":0.0005977323,"domain_scores_codex":[0.9998692,0.00001813945,0.00001030852,0.0000588312,0.00001681891,0.00002675305],"domain_scores_gemma":[0.9998871,0.00003078933,0.00003309362,0.000007897346,0.00001711257,0.00002390701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003296723,0.00005648557,0.8017141,0.0003463862,0.0001493433,0.001574993,0.000645383,0.0004975692,0.167977,0.00009078823,0.0009592853,0.02269196],"study_design_scores_gemma":[0.00003373571,0.0003369402,0.9868817,0.00004887081,0.0001169515,0.002057964,0.0008306279,0.001016403,0.006481356,0.0001754683,0.002005596,0.00001439163],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966856,0.0008706332,0.0003522735,0.00004006777,0.000008468893,0.00001268324,0.001718358,0.00001202642,0.0003000432],"genre_scores_gemma":[0.9960772,0.0003438893,0.0008330579,0.00008088008,0.0000190002,0.00004678976,0.002281168,0.00001037755,0.0003075222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001399245,"threshold_uncertainty_score":0.004680932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01212438392242051,"score_gpt":0.2214922632649494,"score_spread":0.2093678793425289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}