{"id":"W4407850568","doi":"10.1038/s42004-025-01456-8","title":"Rapid peptide synthesis using a methylimidazolium sulfinyl fluoride salt","year":2025,"lang":"en","type":"article","venue":"Communications Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Fluoride; Salt (chemistry); Peptide; Chemistry; Combinatorial chemistry; Inorganic chemistry; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003427068,0.0005754936,0.0003077765,0.0002177771,0.0002683902,0.0002638839,0.0004529059,0.000622015,0.001424676],"category_scores_gemma":[0.0003103329,0.0002139332,0.0002719518,0.0002147532,0.0002021643,0.0003586544,0.0002860441,0.0008027263,0.001022653],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00038379,"about_ca_system_score_gemma":0.0005542862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008168385,"about_ca_topic_score_gemma":0.001782418,"domain_scores_codex":[0.999791,0.00001930695,0.00001911626,0.00004849879,0.00008234626,0.00003981864],"domain_scores_gemma":[0.9998732,0.00002742692,0.00003402049,0.00001621995,0.00002681146,0.00002242152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002981741,0.00001538605,0.00005167448,0.000108329,0.000007781668,0.0001013664,0.00003191537,0.0001358756,0.9948263,0.0003930776,0.0001449032,0.004153532],"study_design_scores_gemma":[0.00001271311,0.0002589448,0.0002414816,0.00001051181,0.000009065553,0.0002061387,0.000006652189,0.0004967803,0.9913762,0.00007374128,0.007297982,0.000009716129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8148077,0.008554221,0.1516724,0.001069141,0.0004495199,0.0006566694,0.001370469,0.001758165,0.01966169],"genre_scores_gemma":[0.8930988,0.005902453,0.08691348,0.0003203441,0.00008080778,0.0002922396,0.0008897877,0.0001158312,0.01238626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001424676,"threshold_uncertainty_score":0.004765987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02358551328217987,"score_gpt":0.2899782815277313,"score_spread":0.2663927682455514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}