{"id":"W4407903569","doi":"10.1016/j.phanu.2025.100438","title":"Opportunities and challenges associated with rheumatoid arthritis: The role of natural polyphenol products","year":2025,"lang":"en","type":"article","venue":"PharmaNutrition","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China","keywords":"Rheumatoid arthritis; Polyphenol; Natural (archaeology); Business; Medicine; Traditional medicine; Biology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000146746,0.00009618481,0.000111777,0.00003528635,0.00008782768,0.00001476097,0.00007586933,0.00004562166,0.000002634966],"category_scores_gemma":[0.00006611074,0.00006728111,0.00002412338,0.00005439487,0.000135743,0.000009441341,0.00004230642,0.00006942455,1.722787e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006096363,"about_ca_system_score_gemma":0.00002778102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001327512,"about_ca_topic_score_gemma":0.00001839846,"domain_scores_codex":[0.9994375,0.00007107672,0.0001087869,0.0001841121,0.00008155634,0.0001170032],"domain_scores_gemma":[0.9996486,0.00002544423,0.00006676163,0.0001403833,0.000103028,0.00001581172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000375891,0.0002010746,0.0002570297,0.0001468429,0.0003185328,0.000001883085,0.0001716058,6.215805e-7,0.7819982,0.003078911,0.001193658,0.2122558],"study_design_scores_gemma":[0.0005533742,0.00009960578,0.001144442,0.0001434931,0.00001864471,0.00001229683,0.001447426,0.00001917641,0.9624663,0.000538522,0.03343973,0.000116981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.767039,0.2253404,0.000002690585,0.006351422,0.00007483084,0.000216962,0.00002399451,0.00001328481,0.0009374315],"genre_scores_gemma":[0.924378,0.07520124,0.0000281128,0.00008886091,0.00005472713,0.00002286701,0.00005120003,0.0000065424,0.0001684899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2121388,"threshold_uncertainty_score":0.2743644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01915977483722006,"score_gpt":0.2249082538577375,"score_spread":0.2057484790205175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}