{"id":"W4407920904","doi":"10.1038/s41598-025-91100-1","title":"The MiR-139-5p and CXCR4 axis may play a role in high glucose-induced inflammation by regulating monocyte migration","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Inflammation; Monocyte; CXCR4; Cell biology; Biology; Immunology; Cancer research; Chemokine; Bioinformatics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003307727,0.0004656447,0.0003390478,0.0002515878,0.0002915932,0.000576295,0.0002364463,0.0003933503,0.002627664],"category_scores_gemma":[0.0002445779,0.0001695197,0.0004427618,0.0002314317,0.0002740465,0.0002740549,0.0002941388,0.0006853445,0.0004496331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003924076,"about_ca_system_score_gemma":0.000640893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007803285,"about_ca_topic_score_gemma":0.000735753,"domain_scores_codex":[0.9996511,0.00007444675,0.00003436451,0.00006639129,0.00009243796,0.00008131569],"domain_scores_gemma":[0.9998719,0.00001733815,0.00004795223,0.000007014298,0.00002830685,0.00002761378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007674037,0.0001041409,0.002945642,0.0003897775,0.00005228836,0.000491263,0.00005751917,0.0001578299,0.9808297,0.001685771,0.0007209654,0.0117977],"study_design_scores_gemma":[0.0001252328,0.0008559083,0.06684539,0.0000990894,0.0002155594,0.001803093,0.0002141076,0.002916545,0.8907869,0.0009859739,0.03511325,0.00003893311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9227433,0.03874528,0.02145846,0.00150312,0.0008918063,0.0001756675,0.002183693,0.0004742644,0.01182435],"genre_scores_gemma":[0.9774489,0.007304374,0.008906506,0.0004908686,0.0001002648,0.0001475311,0.00116436,0.00005722085,0.004380053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002627664,"threshold_uncertainty_score":0.008790433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005236212602401622,"score_gpt":0.2346661215873659,"score_spread":0.2294299089849642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}