{"id":"W4407924517","doi":"10.3390/v17030312","title":"Dynamics of a Panzootic: Genomic Insights, Host Range, and Epidemiology of the Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b in the United States","year":2025,"lang":"en","type":"review","venue":"Viruses","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; St. Jude Children's Research Hospital","keywords":"Influenza A virus subtype H5N1; Clade; Outbreak; Biology; Transmission (telecommunications); Virus; Virology; Host (biology); Highly pathogenic; Influenza A virus; Epidemiology; Lineage (genetic); Avian influenza virus; Zoology; Phylogenetics; Genetics; Medicine; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001230859,0.0005587924,0.003110987,0.0009654338,0.0001314319,0.000009428249,0.0007600446,0.000443708,0.00001093361],"category_scores_gemma":[0.00420978,0.0002770282,0.000465756,0.00166415,0.001199034,0.00005060792,0.0006193893,0.001103165,0.000008275649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002495408,"about_ca_system_score_gemma":0.0006520156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002193215,"about_ca_topic_score_gemma":0.001010659,"domain_scores_codex":[0.9944556,0.002391385,0.001745367,0.0004873872,0.0003707177,0.0005494836],"domain_scores_gemma":[0.9911795,0.00657102,0.0008431275,0.001116249,0.0002094988,0.00008060638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001636662,0.00163285,0.3591639,0.2703356,0.008187662,0.0002374577,0.01027471,0.0001152279,0.0002706652,0.02558835,0.002385147,0.3201717],"study_design_scores_gemma":[0.001684953,0.00038924,0.07968734,0.02485893,0.002417803,0.00003643932,0.0005456586,0.00007334111,0.00001324148,0.0006971828,0.8891451,0.0004507876],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03783207,0.9585886,0.000004137162,0.0002733256,0.00009343866,0.0022829,0.0007902643,0.00002079616,0.0001144433],"genre_scores_gemma":[0.0008315904,0.9958413,0.00007773133,0.002812274,0.00005755136,0.0001936506,0.00008789661,0.00004808437,0.00004991502],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8867599,"threshold_uncertainty_score":0.9999682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1542152765911934,"score_gpt":0.4224797417820111,"score_spread":0.2682644651908176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}