{"id":"W4407955028","doi":"10.1016/j.nutres.2025.02.004","title":"Yeast mannans promote laxation and specifically modulate microbiota composition in older adults: An open-label pilot study","year":2025,"lang":"en","type":"article","venue":"Nutrition Research","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lallemand (Canada)","funders":"National Institute of Food and Agriculture; Department of Food Science and Human Nutrition, College of Agriculture and Natural Resources, Michigan State University; Institute of Food and Agricultural Sciences, University of Florida; Lallemand; University of Florida","keywords":"Yeast; Food science; Gerontology; Biology; Psychology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009925866,0.001034661,0.00190384,0.0002916057,0.0004548916,0.0005394667,0.0004290297,0.00100283,0.003769133],"category_scores_gemma":[0.0007411498,0.0003898825,0.001092997,0.0002367964,0.0005235139,0.0006511472,0.0004850002,0.001582527,0.0004280987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003088582,"about_ca_system_score_gemma":0.0006497558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005696795,"about_ca_topic_score_gemma":0.00148777,"domain_scores_codex":[0.999671,0.0001125539,0.00003182889,0.00007467208,0.00004359935,0.00006631365],"domain_scores_gemma":[0.9995182,0.0000851937,0.00009833465,0.0000462222,0.00007314569,0.0001790292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5808571,0.2722439,0.002541351,0.002733704,0.001098526,0.0001393232,0.0003761621,0.0003439384,0.08771265,0.0001110897,0.0008533657,0.05098889],"study_design_scores_gemma":[0.04512596,0.9379403,0.008863634,0.0001019317,0.0005107111,0.00004290899,0.000136458,0.0003523686,0.00548223,0.00007091079,0.001350162,0.00002240134],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963509,0.001129443,0.0004144341,0.00008828146,0.00008358232,0.001374096,0.0002515502,0.00003279314,0.0002749643],"genre_scores_gemma":[0.9867069,0.002192504,0.003095019,0.0003874839,0.0001503127,0.00454211,0.0004831383,0.00001586511,0.002426714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003769133,"threshold_uncertainty_score":0.012609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06652740813749176,"score_gpt":0.3996936696044952,"score_spread":0.3331662614670035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}