{"id":"W4407956694","doi":"10.1038/s41586-025-08633-8","title":"Programs, origins and immunomodulatory functions of myeloid cells in glioma","year":2025,"lang":"en","type":"article","venue":"Nature","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Cancer Institute","keywords":"Glioma; Myeloid; Myeloid cells; Biology; Cancer research; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001028407,0.0001494161,0.0001731425,0.0002082303,0.0001159271,0.0002943893,0.0001325363,0.0001402504,0.0003973076],"category_scores_gemma":[0.000214363,0.00008760427,0.0002216578,0.0002484633,0.0002544665,0.0001855637,0.0001595689,0.0001807761,0.00008090195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002964242,"about_ca_system_score_gemma":0.0002756781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001229655,"about_ca_topic_score_gemma":0.002056054,"domain_scores_codex":[0.9999592,0.000006419625,0.00000164622,0.00001476244,0.0000093697,0.000008556101],"domain_scores_gemma":[0.9999455,0.00002160194,0.00001586994,0.000005772508,0.000005459097,0.000005759575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003827875,0.00003847876,0.0350394,0.0003044253,0.00004798418,0.0001693652,0.0001743306,0.09355407,0.8206869,0.01024208,0.000198451,0.03916166],"study_design_scores_gemma":[0.00003735533,0.0004486077,0.1242114,0.00004822978,0.0001578215,0.000488,0.000430824,0.4678766,0.3749186,0.02060773,0.01070727,0.00006741619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9761752,0.0008520446,0.02139487,0.00003925049,0.000003866038,0.00001232789,0.0005102397,0.00009634809,0.0009159006],"genre_scores_gemma":[0.984071,0.0007213558,0.01438358,0.00001171777,0.000003250602,0.00001525563,0.0004761649,0.00002193138,0.0002957063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001229655,"threshold_uncertainty_score":0.002444983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004224624008638103,"score_gpt":0.2353990578725146,"score_spread":0.2311744338638765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}