{"id":"W4407968838","doi":"10.21873/invivo.13886","title":"A New Approach to Highly Conformal Hippocampal-sparing Whole-brain Radiotherapy: A Feasibility Study","year":2025,"lang":"en","type":"article","venue":"In Vivo","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Hippocampal formation; Whole brain radiotherapy; Radiation therapy; Medicine; Conformal map; Neuroscience; Internal medicine; Psychology; Mathematics; Cancer; Brain metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005805162,0.0001870448,0.0004345553,0.0002066086,0.00004897827,0.0000375426,0.0001210927,0.00005869695,0.00009988902],"category_scores_gemma":[0.00009295388,0.0001525036,0.00008802058,0.0004848021,0.00002102057,0.00005561688,0.00006078282,0.0001682598,0.00002198795],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002804658,"about_ca_system_score_gemma":0.0002196625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009934937,"about_ca_topic_score_gemma":0.0001826568,"domain_scores_codex":[0.9986507,0.0000947033,0.0003215355,0.0004121636,0.000214841,0.000306082],"domain_scores_gemma":[0.9991066,0.00009602663,0.00003533044,0.0005482186,0.00002755916,0.000186236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003869227,0.01120375,0.7643076,0.0004008298,0.001219438,0.0003136892,0.0143707,0.0006383365,0.003480513,0.004624035,0.0829813,0.1125906],"study_design_scores_gemma":[0.04325594,0.003347222,0.7915221,0.0004319132,0.0004077839,0.00006212028,0.006271237,0.001674197,0.001674652,0.0007717159,0.1498966,0.0006844779],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.96659,0.0003076134,0.007084981,0.005971412,0.0001787252,0.002770219,0.00001184976,0.00007965393,0.01700553],"genre_scores_gemma":[0.9786108,0.000002035673,0.01003732,0.002373298,0.00008008866,0.0001147601,0.000007309863,0.00001557248,0.008758859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1119061,"threshold_uncertainty_score":0.6218918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03324322189570626,"score_gpt":0.3304777267690199,"score_spread":0.2972345048733136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}