{"id":"W4407973233","doi":"10.1001/jamacardio.2025.0016","title":"Finerenone and Outpatient Worsening Heart Failure With Mildly Reduced or Preserved Ejection Fraction","year":2025,"lang":"en","type":"article","venue":"JAMA Cardiology","topic":"Heart Failure Treatment and Management","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Heart, Lung, and Blood Institute","keywords":"Medicine; Ejection fraction; Diuretic; Heart failure; Internal medicine; Loop diuretic; Outpatient clinic; Randomized controlled trial; Placebo; Cardiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001633511,0.0001395584,0.0003928411,0.0001642502,0.00009038208,0.00002020894,0.00002401674,0.0001504364,0.00004437162],"category_scores_gemma":[0.00009769253,0.00009343576,0.00005658496,0.0002014494,0.00004816923,0.00008365447,0.00004466058,0.0001971069,0.0000146148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008648606,"about_ca_system_score_gemma":0.00006097318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001059896,"about_ca_topic_score_gemma":0.00008628442,"domain_scores_codex":[0.9991069,0.00011537,0.0001647854,0.0003054723,0.0001003016,0.0002071169],"domain_scores_gemma":[0.999503,0.0000802939,0.00003916251,0.0002346094,0.0000787281,0.00006425493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006883772,0.000242491,0.5390641,0.0004057757,0.002203817,0.0003055447,0.0002626585,0.0002152614,0.01166308,0.0004553784,0.4196975,0.01860064],"study_design_scores_gemma":[0.004748726,0.001551813,0.2624496,0.0002069069,0.0005261109,0.000133541,0.0006714699,0.0001529322,0.001205994,0.00003672268,0.7281586,0.0001576125],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9685791,0.0001659645,0.001698507,0.02399256,0.0002333,0.0008363645,0.000002352892,0.0001195832,0.004372237],"genre_scores_gemma":[0.9885767,0.00004032439,0.005127484,0.0006014592,0.0002089707,0.0001167169,0.00004868022,0.00001196983,0.005267772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3084611,"threshold_uncertainty_score":0.3810199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01619590724561353,"score_gpt":0.2715499344412939,"score_spread":0.2553540271956804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}