{"id":"W4407992872","doi":"10.1021/acs.jnatprod.4c01132","title":"Gymnopeptides C and D, Highly <i>N</i>-Methylated Fungal Cyclopeptides","year":2025,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Drug Research and Development","funders":"Nemzeti Kutatási Fejlesztési és Innovációs Hivatal","keywords":"Stereochemistry; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004699894,0.0002721884,0.000111992,0.0001858263,0.0001208678,0.0001795295,0.0001339142,0.0002022416,0.00177079],"category_scores_gemma":[0.0001253186,0.00005896001,0.0001385321,0.0001980775,0.0001769375,0.0001666332,0.0001699534,0.0003423379,0.0002998767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002230028,"about_ca_system_score_gemma":0.000200068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000485627,"about_ca_topic_score_gemma":0.0006433265,"domain_scores_codex":[0.9999613,0.000004582224,0.000002924262,0.00001249058,0.00000940823,0.000009279239],"domain_scores_gemma":[0.9999357,0.000009613438,0.00001461625,0.00000663215,0.000007921876,0.00002542188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002776564,0.00001646642,0.0002866568,0.00006974693,0.000006237136,0.0001727109,0.00001613109,0.0001684773,0.9925281,0.0003937789,0.00006226393,0.00600182],"study_design_scores_gemma":[0.00004784351,0.0005447862,0.008366814,0.00001857078,0.00002062516,0.0008044521,0.00004839681,0.0004508281,0.9763168,0.000388736,0.01297458,0.00001753659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9808195,0.003962819,0.004696422,0.0002162777,0.00006939865,0.00008914558,0.001367577,0.00005698204,0.008721812],"genre_scores_gemma":[0.9901057,0.001617678,0.005207781,0.0001286557,0.00001603527,0.00003134298,0.0007879545,0.000009223391,0.002095782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00177079,"threshold_uncertainty_score":0.005923927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007627251014780186,"score_gpt":0.2479663845525323,"score_spread":0.2403391335377521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}