{"id":"W4408055348","doi":"10.1021/acsomega.4c07425","title":"“Allergolds”: Gold Nanocluster-Based Bioconjugates of Food Allergens with Reduced Immunoglobulin E Binding","year":2025,"lang":"en","type":"article","venue":"ACS Omega","topic":"Nanocluster Synthesis and Applications","field":"Materials Science","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Acadia University; St. Francis Xavier University","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Research Nova Scotia; National Institute of Environmental Health Sciences; Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases; St. Francis Xavier University","keywords":"Antibody; Chemistry; Food protein; Immunoglobulin G; Colloidal gold; Nanotechnology; Biochemistry; Immunology; Biology; Materials science; Nanoparticle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001270628,0.0003771227,0.0001691931,0.0001657427,0.0000866923,0.0001817155,0.0003385564,0.0004960624,0.0008495059],"category_scores_gemma":[0.0001457933,0.0001589536,0.0002103284,0.00007352042,0.000178317,0.0002506805,0.0003165105,0.0002416635,0.0003032936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002570648,"about_ca_system_score_gemma":0.0001261565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003375595,"about_ca_topic_score_gemma":0.0005735677,"domain_scores_codex":[0.9998783,0.00001756513,0.000008577974,0.00003420626,0.00003733654,0.00002397793],"domain_scores_gemma":[0.9999416,0.000007946287,0.00002197451,0.000007933097,0.000008789054,0.00001177159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002776509,0.00001897858,0.00007176986,0.00004920652,0.00000593731,0.00006950815,0.00001038303,0.0001559501,0.9971409,0.0001388092,0.0001244223,0.002186296],"study_design_scores_gemma":[0.000004584066,0.0001986917,0.0004866282,0.000003393418,0.000007163115,0.0001709937,0.000006767474,0.0008985224,0.9959843,0.00002898872,0.002203855,0.000006174409],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9795615,0.001336057,0.01529147,0.0001739273,0.00007364588,0.0000672395,0.0001945921,0.0004905118,0.002811044],"genre_scores_gemma":[0.9801354,0.0006021918,0.01351032,0.0002707892,0.00001454797,0.00004141921,0.0002258398,0.00004802812,0.005151449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008495059,"threshold_uncertainty_score":0.00284189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01210856470946721,"score_gpt":0.2363409255996994,"score_spread":0.2242323608902322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}