{"id":"W4408055348","doi":"10.1021/acsomega.4c07425","title":"“Allergolds”: Gold Nanocluster-Based Bioconjugates of Food Allergens with Reduced Immunoglobulin E Binding","year":2025,"lang":"en","type":"article","venue":"ACS Omega","topic":"Nanocluster Synthesis and Applications","field":"Materials Science","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Acadia University; St. Francis Xavier University","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Research Nova Scotia; National Institute of Environmental Health Sciences; Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases; St. Francis Xavier University","keywords":"Antibody; Chemistry; Food protein; Immunoglobulin G; Colloidal gold; Nanotechnology; Biochemistry; Immunology; Biology; Materials science; Nanoparticle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000266808,0.0002075932,0.000322674,0.0001874261,0.0001404646,0.00007694973,0.0005442662,0.00009577313,0.0000561007],"category_scores_gemma":[0.00004577345,0.0001661282,0.00007655084,0.0005664388,0.000144202,0.0001234052,0.0001270016,0.0000738365,0.00007540052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004970689,"about_ca_system_score_gemma":0.0001864136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000558832,"about_ca_topic_score_gemma":0.00005742951,"domain_scores_codex":[0.9985584,0.00005807977,0.0004294119,0.0004048219,0.0002194887,0.0003298167],"domain_scores_gemma":[0.9987806,0.0001676817,0.0002039333,0.0006624542,0.0001250229,0.00006031574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006965309,0.0001321668,0.0001611171,0.00005801463,0.0000416991,0.000001007104,0.00007710798,0.00009295833,0.9955139,0.002254031,0.001141654,0.0004566794],"study_design_scores_gemma":[0.0006716384,0.0001571144,0.00040868,0.0001850879,0.00003663963,0.000001714905,0.0001075684,0.00004828865,0.9919871,0.0001980926,0.00600183,0.0001962234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947298,0.0002795513,0.001055913,0.001003719,0.0001934566,0.0003966338,0.00007056811,0.000101829,0.002168562],"genre_scores_gemma":[0.9933384,0.00001802364,0.004826743,0.0001656832,0.00002959156,0.0001333847,0.00001446148,0.00002201656,0.001451718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004860176,"threshold_uncertainty_score":0.6774511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01210856470946721,"score_gpt":0.2363409255996994,"score_spread":0.2242323608902322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}