{"id":"W4408065122","doi":"10.1016/j.lungcan.2025.108334","title":"225 Durvalumab (D) as consolidation therapy in limited-stage SCLC (LS-SCLC): Outcomes by prior concurrent chemoradiotherapy (cCRT) regimen and prophylactic cranial irradiation (PCI) use in the ADRIATIC trial","year":2025,"lang":"en","type":"article","venue":"Lung Cancer","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"AstraZeneca (Canada)","funders":"","keywords":"Medicine; Prophylactic cranial irradiation; Durvalumab; Regimen; Oncology; Chemoradiotherapy; Conventional PCI; Internal medicine; Radiation therapy; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000887989,0.0005544081,0.001248905,0.000153891,0.0002042984,0.0009606159,0.0004413596,0.0004281344,0.001363794],"category_scores_gemma":[0.0009109626,0.0002178739,0.001711844,0.0002717745,0.0003805557,0.0004886911,0.000308128,0.001377003,0.0002517159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008763833,"about_ca_system_score_gemma":0.0007775038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002828524,"about_ca_topic_score_gemma":0.005518747,"domain_scores_codex":[0.9995601,0.0002241556,0.00003284782,0.00006255384,0.00003580905,0.00008445602],"domain_scores_gemma":[0.9994784,0.000116588,0.0001370586,0.00005506525,0.00003263339,0.0001803247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.882997,0.002926768,0.03701225,0.0006415939,0.008079928,0.00009742132,0.00007927249,0.001034464,0.004067577,0.0003568431,0.002215714,0.0604911],"study_design_scores_gemma":[0.5041981,0.1807667,0.2738432,0.0003784595,0.02028068,0.0004549488,0.0003325978,0.00379055,0.004667104,0.001212774,0.009971686,0.000103278],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924616,0.005576192,0.00008835211,0.000247326,0.0001067128,0.0001024022,0.0004281907,0.00001072181,0.0009786004],"genre_scores_gemma":[0.996731,0.001486477,0.0001222103,0.0002936648,0.00009137379,0.00005409207,0.0006340711,0.000002794087,0.0005841808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002828524,"threshold_uncertainty_score":0.006358624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03159646343939662,"score_gpt":0.39573207681587,"score_spread":0.3641356133764734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}