{"id":"W4408098247","doi":"10.1186/s13567-025-01465-4","title":"Piggybacking on nature: exploring the multifaceted world of porcine β-defensins","year":2025,"lang":"en","type":"review","venue":"Veterinary Research","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Ministry of Agriculture - Saskatchewan","keywords":"Biology; Innate immune system; Computational biology; Clinical trial; Antimicrobial; Antimicrobial peptides; Immune system; Immunology; Bioinformatics; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000373175,0.0006251685,0.0006912895,0.001422492,0.0001846669,0.0009776205,0.0004811442,0.0008420071,0.002319745],"category_scores_gemma":[0.0003846274,0.0001792215,0.0003257779,0.001036776,0.0003127452,0.001164255,0.0005403143,0.001406326,0.001259106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003273533,"about_ca_system_score_gemma":0.000598003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003484624,"about_ca_topic_score_gemma":0.0006204436,"domain_scores_codex":[0.9999031,0.00001667912,0.00001106409,0.00001980674,0.00003664928,0.00001276235],"domain_scores_gemma":[0.9998615,0.00007295614,0.00001871745,0.00000458313,0.00002747849,0.00001473572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008474986,0.00006409462,0.0001708683,0.0162743,0.00006663483,0.0002681261,0.00011102,0.0002600193,0.008475071,0.005533291,0.01555254,0.9531392],"study_design_scores_gemma":[0.000009910847,0.0001463992,0.000710369,0.002980245,0.00006087299,0.001293284,0.00008319272,0.00006343949,0.001246731,0.001781024,0.9916092,0.00001537545],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003126933,0.9974855,0.0002042852,0.000239625,0.0002819904,0.000004448979,0.00001634458,0.000006889412,0.001448307],"genre_scores_gemma":[0.001067912,0.997465,0.0002664862,0.0002350544,0.0001449752,0.000006256025,0.00003161071,0.000001794907,0.0007808502],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002319745,"threshold_uncertainty_score":0.007760346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3139889090902113,"score_gpt":0.4466320587603947,"score_spread":0.1326431496701834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}