{"id":"W4408110395","doi":"10.1038/s41577-025-01154-5","title":"Type 1 immune response reduces seizure risk after traumatic brain injury","year":2025,"lang":"en","type":"review","venue":"Nature reviews. Immunology","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Disability Prevention and Rehabilitation; University of Toronto","funders":"","keywords":"Traumatic brain injury; Immune system; Medicine; Immunology; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.001920779,0.001091769,0.003430378,0.0009795488,0.0003404814,0.0001434079,0.001393161,0.001904717,0.0006862638],"category_scores_gemma":[0.01676493,0.0008455119,0.001134886,0.002269561,0.0001974167,0.0002198386,0.0003671194,0.004468992,0.001893348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001511254,"about_ca_system_score_gemma":0.0006952934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001009681,"about_ca_topic_score_gemma":0.000001136046,"domain_scores_codex":[0.9837507,0.01155206,0.002167288,0.001496924,0.0003807034,0.0006523161],"domain_scores_gemma":[0.9935897,0.002674167,0.00167692,0.001832564,0.0001207947,0.0001058342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003679736,0.00008066955,2.079004e-8,0.006965376,0.00005521032,0.00009440663,0.00006751207,1.463252e-7,0.01199344,0.001046577,0.01392591,0.9654028],"study_design_scores_gemma":[0.0002043462,0.0002239999,0.000002083417,0.008934778,0.0003597191,0.0002564963,0.000003010426,0.00000199492,0.005642817,0.0001042258,0.9836432,0.0006233437],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001736609,0.991194,0.00002543173,0.0005980759,0.004210865,0.003009883,0.0002151611,0.0002780195,0.0002949476],"genre_scores_gemma":[0.00003040035,0.9867554,0.0002427026,0.002301528,0.0001847371,0.0006332924,0.00007693903,0.0001157903,0.00965922],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9697173,"threshold_uncertainty_score":0.9993995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04306386073406415,"score_gpt":0.3686470381780746,"score_spread":0.3255831774440104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}