{"id":"W4408114987","doi":"10.7554/elife.103245.2.sa0","title":"Author response: CCR5 antagonists as cerebroprotective and stroke recovery enhancing agents: a preclinical systematic review and meta-analysis","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"","keywords":"Meta-analysis; Stroke (engine); Medicine; Psychology; Pharmacology; Internal medicine; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02126701,0.002455102,0.0133614,0.00513201,0.000503914,0.003090128,0.002379148,0.004325093,0.03111131],"category_scores_gemma":[0.09644789,0.001390533,0.01650929,0.00646273,0.0007917296,0.003705628,0.002044699,0.002910442,0.002773061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004915275,"about_ca_system_score_gemma":0.006477115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00694843,"about_ca_topic_score_gemma":0.01408274,"domain_scores_codex":[0.9840141,0.006624691,0.005200184,0.001553621,0.002018742,0.0005886643],"domain_scores_gemma":[0.9569426,0.02909247,0.007729115,0.0007696053,0.005005156,0.0004610718],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001227613,0.00001219187,0.001185158,0.9094897,0.05436018,0.00009987492,0.00009750366,0.0002412378,0.0001275793,0.0002808607,0.02043691,0.01244123],"study_design_scores_gemma":[0.007149804,0.0004343522,0.00932757,0.5684128,0.3688487,0.0003617725,0.0003144123,0.0004011864,0.0003982603,0.002183812,0.04202626,0.0001409394],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.004848022,0.9185005,0.002910797,0.03176885,0.005812873,0.006556612,0.02545687,0.0003020263,0.003843472],"genre_scores_gemma":[0.1558974,0.6837845,0.007133079,0.1010888,0.004856305,0.02791607,0.01012306,0.0004355629,0.008765207],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.03111131,"threshold_uncertainty_score":0.1124721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1347183573050911,"score_gpt":0.402089592098185,"score_spread":0.2673712347930939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}