{"id":"W4408158680","doi":"10.3389/frmbi.2025.1454909","title":"Probiotic supplementation prevents stress-impaired spatial learning and enhances the effects of environmental enrichment","year":2025,"lang":"en","type":"article","venue":"Frontiers in Microbiomes","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Probiotic; Environmental stress; Environmental enrichment; Spatial learning; Stress (linguistics); Psychology; Food science; Biology; Neuroscience; Ecology; Cognition; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008396921,0.0004699646,0.0005009708,0.0002121251,0.0001426403,0.0002115612,0.0001804886,0.0002600731,0.0009486864],"category_scores_gemma":[0.0001988918,0.0001218744,0.0002343357,0.0001237936,0.0002279433,0.0001767352,0.0002917567,0.000586858,0.0001542938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001304322,"about_ca_system_score_gemma":0.0003727031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001002313,"about_ca_topic_score_gemma":0.002745383,"domain_scores_codex":[0.9999089,0.00001390485,0.000009191815,0.00001790608,0.00001586927,0.00003418983],"domain_scores_gemma":[0.9998336,0.000009602067,0.00004905502,0.00001589055,0.00001849906,0.00007332573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005611043,0.0007715986,0.001532294,0.0001961864,0.00005919457,0.00007380097,0.00005912157,0.00006647014,0.9753155,0.00004801803,0.0001058631,0.01616097],"study_design_scores_gemma":[0.0003095286,0.0231147,0.1090271,0.000141794,0.0002960708,0.0002343015,0.0004245759,0.000894332,0.8609435,0.0004500342,0.00412252,0.00004151316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983035,0.0008208926,0.0003456061,0.0000643903,0.00002894741,0.00000735576,0.0001174352,0.00003087454,0.0002809684],"genre_scores_gemma":[0.9964508,0.001188704,0.0008511223,0.0000653229,0.00002023925,0.00002941785,0.0002485686,0.00001260899,0.001133162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001002313,"threshold_uncertainty_score":0.003173709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00343096854445456,"score_gpt":0.2317551985180357,"score_spread":0.2283242299735812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}