{"id":"W4408184519","doi":"10.1021/acsnano.4c17291","title":"Starfish-Inspired Synergistic Reinforced Hydrogel Wound Dressing: Dual Responsiveness and Enhanced Bioactive Compound Delivery for Advanced Skin Regeneration and Management","year":2025,"lang":"en","type":"article","venue":"ACS Nano","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"H2020 European Research Council; National Key Research and Development Program of China; State Key Laboratory of Polymer Materials Engineering; China Postdoctoral Science Foundation; Canada Foundation for Innovation; National Natural Science Foundation of China; Canada Excellence Research Chairs, Government of Canada","keywords":"Starfish; Regeneration (biology); Wound dressing; Wound healing; Self-healing hydrogels; Biomedical engineering; Materials science; Nanotechnology; Chemistry; Medicine; Surgery; Cell biology; Polymer chemistry; Biology; Composite material","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001312036,0.0002999608,0.0001954677,0.0002057687,0.00009333754,0.0002134941,0.000188681,0.0003259864,0.0004798995],"category_scores_gemma":[0.00008996782,0.0001323559,0.0002653378,0.0001227251,0.000125673,0.0002663278,0.000286025,0.0002508876,0.0001542539],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001611941,"about_ca_system_score_gemma":0.0001832993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002069177,"about_ca_topic_score_gemma":0.0005539045,"domain_scores_codex":[0.9999224,0.000008399284,0.000007785831,0.00001901645,0.00002760822,0.00001483006],"domain_scores_gemma":[0.9999415,0.00000711443,0.00001933626,0.000004083175,0.00001006494,0.00001805238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002762165,0.00001534188,0.00005928631,0.00006824717,0.00000276764,0.0000402072,0.000008522288,0.0000967165,0.9973916,0.00004571327,0.00002645068,0.002217598],"study_design_scores_gemma":[0.0000105185,0.0002981506,0.0007645661,0.00000674411,0.00001521549,0.0002760383,0.0000161918,0.002203108,0.9945374,0.00002932454,0.001832085,0.00001054973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758803,0.003979618,0.01824111,0.0001083921,0.00006650743,0.00006363213,0.0001260017,0.0001183929,0.001416026],"genre_scores_gemma":[0.9853138,0.001397304,0.01123409,0.00008269105,0.00001160549,0.00003493738,0.00007598028,0.00001900886,0.001830607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004798995,"threshold_uncertainty_score":0.001605451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0148510270657018,"score_gpt":0.2906532964951001,"score_spread":0.2758022694293983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}