{"id":"W4408184850","doi":"10.1007/s00270-025-03994-z","title":"Multicenter, PrOspective, Randomized, Controlled Trial Comparing GenIcular Artery EmbOlization Using Embosphere Microspheres to Corticosteroid iNjections for the Treatment of Symptomatic Knee Osteoarthritis: MOTION Study Protocol Summary","year":2025,"lang":"en","type":"article","venue":"CardioVascular and Interventional Radiology","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Merit Medical Systems; Northwestern University","keywords":"Medicine; Osteoarthritis; Randomized controlled trial; Embolization; Surgery; Microsphere; Radiology; Ultrasound; Corticosteroid; Multicenter trial; Prospective cohort study; Multicenter study; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007539844,0.004299612,0.006801,0.0007865154,0.001305638,0.002127373,0.001841971,0.004171877,0.021015],"category_scores_gemma":[0.009417953,0.001335379,0.003371661,0.001187307,0.001399943,0.001827766,0.0007841666,0.003979347,0.003216166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001566058,"about_ca_system_score_gemma":0.005608071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001607773,"about_ca_topic_score_gemma":0.003526919,"domain_scores_codex":[0.995694,0.002437699,0.0004299117,0.0005848009,0.0004113503,0.0004421145],"domain_scores_gemma":[0.9950318,0.001246935,0.001822815,0.0003285025,0.0007360254,0.0008339263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9871871,0.003155435,0.0007271844,0.002039069,0.001633417,0.00002836469,0.00003372575,0.0001778255,0.0005588039,0.0001382828,0.00133613,0.00298457],"study_design_scores_gemma":[0.9797711,0.01640452,0.001305701,0.0001452856,0.0008618712,0.00001258607,0.00001544361,0.0003045132,0.0001685866,0.0001194991,0.0008762301,0.00001477431],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.368383,0.01472736,0.004898532,0.003401648,0.003449368,0.5802491,0.01559363,0.0006238526,0.008673401],"genre_scores_gemma":[0.3095829,0.004344386,0.008624733,0.004009602,0.001351808,0.6580613,0.005844971,0.00007063238,0.008109814],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.021015,"threshold_uncertainty_score":0.07030213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01739940801111125,"score_gpt":0.3044278954025916,"score_spread":0.2870284873914803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}