{"id":"W4408184850","doi":"10.1007/s00270-025-03994-z","title":"Multicenter, PrOspective, Randomized, Controlled Trial Comparing GenIcular Artery EmbOlization Using Embosphere Microspheres to Corticosteroid iNjections for the Treatment of Symptomatic Knee Osteoarthritis: MOTION Study Protocol Summary","year":2025,"lang":"en","type":"article","venue":"CardioVascular and Interventional Radiology","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Merit Medical Systems; Northwestern University","keywords":"Medicine; Osteoarthritis; Randomized controlled trial; Embolization; Surgery; Microsphere; Radiology; Ultrasound; Corticosteroid; Multicenter trial; Prospective cohort study; Multicenter study; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005564597,0.0002523932,0.001824032,0.0001242035,0.0002077995,0.00003760375,0.00005648622,0.00009435755,0.00001915416],"category_scores_gemma":[0.0001657183,0.0001691629,0.001991431,0.0001330193,0.0001203425,0.00006920699,0.00003211082,0.00006162164,0.000001075218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001577516,"about_ca_system_score_gemma":0.00006048376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003110081,"about_ca_topic_score_gemma":0.00004266654,"domain_scores_codex":[0.9979057,0.000464438,0.0008620726,0.0003836549,0.0001779023,0.000206187],"domain_scores_gemma":[0.9989116,0.0002654339,0.0001764787,0.0003204682,0.0002646313,0.00006137849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9399692,0.004134063,0.007625492,0.000307633,0.017901,0.0000171268,0.0005510468,0.0009958862,0.001180931,0.0004983937,0.00002653274,0.02679267],"study_design_scores_gemma":[0.9736459,0.01358118,0.001882678,0.0004172342,0.005947215,0.00009026094,0.0005444089,0.002887132,0.0005399836,0.0001405736,0.0001962827,0.000127194],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7298828,0.005815817,0.02968026,0.00001910836,0.0006078906,0.2338755,0.00001052783,0.00003024521,0.00007785212],"genre_scores_gemma":[0.8178918,0.00003195535,0.0005163054,0.00001917481,0.0001385226,0.1811078,0.00003353972,0.00001830692,0.0002426337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08800895,"threshold_uncertainty_score":0.6898263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01739940801111125,"score_gpt":0.3044278954025916,"score_spread":0.2870284873914803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}