{"id":"W4408206414","doi":"10.3389/fcell.2025.1522094","title":"A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression","year":2025,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"National Eye Institute; National Institutes of Health","keywords":"Zebrafish; Expression (computer science); Cell biology; Function (biology); Biology; Computer science; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001587771,0.000840784,0.0002958471,0.0008602291,0.0005187987,0.000288561,0.0004332809,0.0009868866,0.006517326],"category_scores_gemma":[0.0001225392,0.0003266633,0.0004493225,0.0002390228,0.0005987832,0.0002536826,0.0003837429,0.00099662,0.001096883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008333169,"about_ca_system_score_gemma":0.0005495347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004708218,"about_ca_topic_score_gemma":0.009027158,"domain_scores_codex":[0.9998007,0.000008362951,0.00001380315,0.00005804441,0.00008178794,0.00003724324],"domain_scores_gemma":[0.9998032,0.00002044501,0.00007335848,0.00001298469,0.00002289977,0.00006710997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001246084,0.00001969091,0.0004931824,0.0000660808,0.00001248848,0.0009907088,0.00004394947,0.0002109323,0.9957487,0.000389773,0.0004194683,0.001480436],"study_design_scores_gemma":[0.0001052884,0.0004966446,0.02347203,0.00005900859,0.00009785671,0.00576163,0.0001919757,0.003817832,0.951593,0.0003407954,0.01401367,0.0000503244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9650201,0.001123885,0.01435145,0.0008399921,0.0001957628,0.0002117567,0.007999664,0.0009964808,0.009260866],"genre_scores_gemma":[0.9555824,0.0006693263,0.0100349,0.0002880352,0.00001434629,0.0002983074,0.002578884,0.0002140949,0.0303198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006517326,"threshold_uncertainty_score":0.0218026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01635626848451665,"score_gpt":0.2114007481542962,"score_spread":0.1950444796697796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}