{"id":"W4408220093","doi":"10.3390/pathogens14030258","title":"Development of Low-Cost In-House Assays for Quantitative Detection of HBsAg, HBeAg, and HBV DNA to Enhance Hepatitis B Virus Diagnostics and Antiviral Screening in Resource-Limited Settings","year":2025,"lang":"en","type":"article","venue":"Pathogens","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Lethbridge","funders":"","keywords":"HBsAg; Hepatitis B virus; HBeAg; Virology; Viral load; Hepatitis B; Isolation (microbiology); Medicine; Immunology; Virus; Biology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002147899,0.001391517,0.0006868885,0.0007293879,0.0002288477,0.0008089512,0.001114839,0.0009835823,0.001401051],"category_scores_gemma":[0.001898102,0.0006757982,0.0006877807,0.0003837889,0.0003852439,0.000622882,0.0005542366,0.001120757,0.001488273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003679235,"about_ca_system_score_gemma":0.0004940489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004192876,"about_ca_topic_score_gemma":0.0009934703,"domain_scores_codex":[0.9977891,0.0008687057,0.000134919,0.0003411519,0.0007325854,0.000133491],"domain_scores_gemma":[0.9989882,0.0003309606,0.0001866389,0.0001620725,0.0002692184,0.0000628394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005604896,0.0001560898,0.0005208901,0.0001077391,0.00001754431,0.00002626649,0.00002714943,0.0001997835,0.9931115,0.00009429348,0.0001095145,0.005573299],"study_design_scores_gemma":[0.00002249357,0.0004823174,0.001353096,0.00001448695,0.0000332395,0.0001737481,0.00002465192,0.002691587,0.9930084,0.0000424095,0.002141467,0.00001213787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5565875,0.003459127,0.4307241,0.0004681801,0.0003157193,0.001906065,0.001440823,0.001710408,0.003388033],"genre_scores_gemma":[0.5718614,0.002320289,0.413765,0.0004203213,0.0001660398,0.001407323,0.003366467,0.0001662703,0.006526904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002147899,"threshold_uncertainty_score":0.01135933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01982430095068549,"score_gpt":0.3080566473982741,"score_spread":0.2882323464475886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}