{"id":"W4408246537","doi":"10.1182/bloodadvances.2024014858","title":"Transplant outcomes using older matched sibling donors compared with young alternative donors: a CIBMTR analysis","year":2025,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; Office of Naval Research; Legend Biotech; Pharmacyclics; Takeda Oncology; Health Resources and Services Administration; National Institutes of Health; Janssen Research and Development; MorphoSys; Seagen; Swedish Orphan Biovitrum; Vertex Pharmaceuticals; Omeros Corporation; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; Kiadis Pharma; bluebird bio; Medac; Jazz Pharmaceuticals; BeiGene; HistoGenetics; Atara Biotherapeutics; CareDx; Actinium Pharmaceuticals; National Cancer Institute; Gilead Sciences; Sanofi; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; CSL Behring; Bristol-Myers Squibb; AstraZeneca; Gateway for Cancer Research; Alexion Pharmaceuticals; Mallinckrodt Pharmaceuticals; Astellas Pharma US; Amgen","keywords":"Medicine; Internal medicine; Hazard ratio; Calcineurin; Graft-versus-host disease; Cyclophosphamide; Gastroenterology; Transplantation; Proportional hazards model; Immunology; Confidence interval; Chemotherapy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00250183,0.0002562599,0.0004583784,0.0008449499,0.0002566328,0.0007715166,0.0005030828,0.0003276446,0.00362327],"category_scores_gemma":[0.00326784,0.0001417053,0.001376626,0.0009504329,0.0002622498,0.000509635,0.0007317948,0.0006888489,0.0002605675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003650779,"about_ca_system_score_gemma":0.0003537563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001120068,"about_ca_topic_score_gemma":0.001170254,"domain_scores_codex":[0.9985725,0.0004897327,0.0001800407,0.000305439,0.0002569642,0.0001953298],"domain_scores_gemma":[0.9971862,0.0007069068,0.001311898,0.0002189567,0.0001452431,0.0004307143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002725832,0.00009046071,0.9907794,0.000075272,0.001065861,0.0001092345,0.00007666618,0.0001738712,0.0003632686,0.0001304983,0.0002455275,0.004164124],"study_design_scores_gemma":[0.000188924,0.001215822,0.9943346,0.00005543987,0.0009313084,0.0005256415,0.000342865,0.001190311,0.0002722602,0.0001889968,0.0007375337,0.00001624994],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985418,0.0005274658,0.0001726232,0.00003243151,0.00001141647,0.00001136489,0.0003304721,0.000001849601,0.0003705626],"genre_scores_gemma":[0.9994598,0.00008459821,0.00005805739,0.00002884417,0.00001243714,0.000007956355,0.0002675254,0.000001866074,0.00007882255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00362327,"threshold_uncertainty_score":0.0132311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01693444424196785,"score_gpt":0.3049752891689603,"score_spread":0.2880408449269925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}