{"id":"W4408246537","doi":"10.1182/bloodadvances.2024014858","title":"Transplant outcomes using older matched sibling donors compared with young alternative donors: a CIBMTR analysis","year":2025,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; Office of Naval Research; Legend Biotech; Pharmacyclics; Takeda Oncology; Health Resources and Services Administration; National Institutes of Health; Janssen Research and Development; MorphoSys; Seagen; Swedish Orphan Biovitrum; Vertex Pharmaceuticals; Omeros Corporation; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; Kiadis Pharma; bluebird bio; Medac; Jazz Pharmaceuticals; BeiGene; HistoGenetics; Atara Biotherapeutics; CareDx; Actinium Pharmaceuticals; National Cancer Institute; Gilead Sciences; Sanofi; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; CSL Behring; Bristol-Myers Squibb; AstraZeneca; Gateway for Cancer Research; Alexion Pharmaceuticals; Mallinckrodt Pharmaceuticals; Astellas Pharma US; Amgen","keywords":"Medicine; Internal medicine; Hazard ratio; Calcineurin; Graft-versus-host disease; Cyclophosphamide; Gastroenterology; Transplantation; Proportional hazards model; Immunology; Confidence interval; Chemotherapy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001558531,0.0002936187,0.0008354505,0.0006134505,0.0001325615,0.00004535989,0.0001359358,0.00006844552,0.00005766741],"category_scores_gemma":[0.0000127465,0.0002198264,0.0001970953,0.0013132,0.00009579714,0.0002228288,0.00001051473,0.000161614,0.000004137309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004809769,"about_ca_system_score_gemma":0.00009807242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004008306,"about_ca_topic_score_gemma":0.0008130337,"domain_scores_codex":[0.9982606,0.00005895655,0.0004899828,0.0004737654,0.0003805368,0.0003361311],"domain_scores_gemma":[0.9990875,0.0002073188,0.0001656203,0.0003068056,0.0001244426,0.0001083046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002650871,0.0002511055,0.9836206,0.0005290841,0.003403962,0.0001578915,0.002642615,0.003991018,0.004843037,0.0001251883,0.000001320082,0.0001691191],"study_design_scores_gemma":[0.01798434,0.0002685236,0.7783395,0.004113672,0.03593162,0.0002946006,0.006186467,0.01114894,0.1443119,0.0002658054,0.0001015208,0.001053064],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.93367,0.0008198764,0.06284451,0.0002049107,0.0001400555,0.0005276811,0.0000369653,0.0001094672,0.001646553],"genre_scores_gemma":[0.9832941,0.000384109,0.01568662,0.0001746054,0.00003783698,0.00003676761,0.00008267695,0.0000225722,0.0002807119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2052811,"threshold_uncertainty_score":0.896426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01693444424196785,"score_gpt":0.3049752891689603,"score_spread":0.2880408449269925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}