{"id":"W4408246590","doi":"10.1111/tan.70124","title":"The Novel Allele <scp>HLA</scp>‐<scp>DPA1</scp>*02:01:34 Differs From <scp>HLA</scp>‐<scp>DPA1</scp>*02:01:01:02 by a Synonymous Mutation","year":2025,"lang":"en","type":"article","venue":"HLA","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal University Hospital; St. Paul's Hospital; University of Saskatchewan","funders":"","keywords":"Human leukocyte antigen; Allele; Biology; Gene; Genetics; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.001347865,0.001864928,0.001817308,0.0008963412,0.002560076,0.000700396,0.001955167,0.002294746,0.0004783375],"category_scores_gemma":[0.006817578,0.001665127,0.001163856,0.0013917,0.001046718,0.001037162,0.0007799836,0.003255173,0.006429398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008228716,"about_ca_system_score_gemma":0.000519671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001831699,"about_ca_topic_score_gemma":0.0004165609,"domain_scores_codex":[0.9903209,0.00133159,0.002414958,0.002440862,0.0006126318,0.002879023],"domain_scores_gemma":[0.9847383,0.01047817,0.001496157,0.002283031,0.0006698835,0.0003344008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008882802,0.001030639,0.0009896981,0.0001021364,0.001590887,0.00004262352,0.003338353,0.0001121578,0.3057918,0.001016991,0.6825777,0.003318211],"study_design_scores_gemma":[0.005426185,0.0006833267,0.007169655,0.0002450861,0.0006434434,0.00018965,0.01608982,0.0005179206,0.147383,0.0005531483,0.8208457,0.0002530411],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8337904,0.02257395,0.008869532,0.00106879,0.02429366,0.003076117,0.0007056489,0.00168911,0.1039328],"genre_scores_gemma":[0.6217471,0.002789655,0.0002875904,0.004698553,0.0007569113,0.0006863028,0.005428085,0.0003778288,0.363228],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2592952,"threshold_uncertainty_score":0.9994095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008291707438538317,"score_gpt":0.2225078028015991,"score_spread":0.2142160953630608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}