{"id":"W4408285865","doi":"10.1002/biot.202400594","title":"Self‐Produced Brain‐Like ECM From 3D‐Cultured Dermal Fibroblasts Enhances Neuronal Growth and Survival","year":2025,"lang":"en","type":"article","venue":"Biotechnology Journal","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé","keywords":"Extracellular matrix; Cell biology; Neurogenesis; Biology; Neural stem cell; Fibroblast; Regenerative medicine; Induced pluripotent stem cell; Cell culture; Neuroscience; Stem cell; Embryonic stem cell; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000114842,0.0002291267,0.0001420851,0.0001661083,0.00007770272,0.0002855454,0.00009587724,0.0002278994,0.0007960769],"category_scores_gemma":[0.00008789631,0.0001033958,0.0002347933,0.0001213477,0.00009640191,0.0001455257,0.0001500753,0.0002458235,0.0003193266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008913488,"about_ca_system_score_gemma":0.0001016548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003210384,"about_ca_topic_score_gemma":0.0008303014,"domain_scores_codex":[0.9999262,0.00000911233,0.000006012185,0.00001834824,0.0000303919,0.00001002068],"domain_scores_gemma":[0.9999409,0.00001637925,0.0000131896,0.000008771632,0.00001038056,0.00001034973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001099984,0.000007243782,0.0000892422,0.00002505836,0.000002832602,0.00006705018,0.000007748133,0.0001038329,0.9983041,0.00003198903,0.00002722956,0.001322572],"study_design_scores_gemma":[0.000003965754,0.00004734164,0.002220131,0.00000786587,0.00001370207,0.0002621296,0.00001561987,0.001178565,0.9933845,0.00004282863,0.002817889,0.000005485359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9700009,0.002928555,0.02041064,0.00009581898,0.0001020955,0.00004136972,0.0008731546,0.0001892794,0.005358252],"genre_scores_gemma":[0.9813173,0.001923618,0.01344759,0.00007193396,0.00001400295,0.00003697035,0.0006506077,0.00004224446,0.002495557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007960769,"threshold_uncertainty_score":0.002663136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006458437714814861,"score_gpt":0.2398520398054523,"score_spread":0.2333936020906375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}