{"id":"W4408301542","doi":"10.1002/cam4.70749","title":"<scp>PRR11</scp> Promotes Bladder Cancer Growth and Metastasis by Facilitating <scp>G1</scp>/S Progression and Epithelial‐Mesenchymal Transition","year":2025,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Science Foundation of Shandong Province","keywords":"Gene silencing; Cancer research; Bladder cancer; Downregulation and upregulation; Gene knockdown; Epithelial–mesenchymal transition; Metastasis; Cancer; Cell growth; Cell cycle; Biology; Apoptosis; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000276071,0.0003114959,0.0003577075,0.0001171855,0.0001843708,0.00002577102,0.0001021878,0.0002583867,0.00001493413],"category_scores_gemma":[0.0003955383,0.0002625341,0.00005403947,0.0003017013,0.0003670318,0.00001995408,0.0000636859,0.0001897645,6.306173e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005711169,"about_ca_system_score_gemma":0.0001711014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003221938,"about_ca_topic_score_gemma":0.0001111177,"domain_scores_codex":[0.998224,0.0001086364,0.0003635432,0.0006684254,0.0002599304,0.0003754256],"domain_scores_gemma":[0.9991707,0.0001163943,0.0001606775,0.0002176636,0.0001753629,0.0001592022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002557908,0.00003495816,0.001435212,0.0003384771,0.0002887488,0.000002183818,0.001542465,0.0000486862,0.9189578,0.00002482643,0.01724418,0.06005689],"study_design_scores_gemma":[0.003597429,0.0007225227,0.005366683,0.0009635962,0.0005912948,0.00002303502,0.001771955,0.001080332,0.9340476,0.0003084594,0.05137099,0.0001561425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9148331,0.07899483,0.002268736,0.002043393,0.0003856673,0.0006264827,0.000233037,0.00003819388,0.0005765582],"genre_scores_gemma":[0.9869198,0.00954954,0.0003669068,0.0005213313,0.0005520289,0.0003096251,0.0003231469,0.00003827533,0.001419388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07208665,"threshold_uncertainty_score":0.9999827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007595270911551846,"score_gpt":0.2836585693388967,"score_spread":0.2760632984273449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}