{"id":"W4408301787","doi":"10.1016/j.vaccine.2025.126988","title":"SARS-CoV-2 conjugate vaccine elicits robust immune responses that can protect against evolving variants.","year":2025,"lang":"en","type":"article","venue":"Vaccine","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"Bill and Melinda Gates Foundation","keywords":"Immunogenicity; Virology; Antigen; Neutralization; Biology; Adjuvant; Immune system; Antibody; Conjugate vaccine; Neutralizing antibody; Immunology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001923527,0.000491199,0.0002276816,0.0001318595,0.00007416197,0.0002209564,0.0001201634,0.0003610918,0.0009057257],"category_scores_gemma":[0.0001206592,0.0001199425,0.0002148679,0.00009090775,0.0001283897,0.0001917724,0.0001752808,0.0005133408,0.0003530483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002046905,"about_ca_system_score_gemma":0.0001261515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000188662,"about_ca_topic_score_gemma":0.0003416812,"domain_scores_codex":[0.9998721,0.00002078304,0.000007936412,0.00002595181,0.00004362546,0.0000296005],"domain_scores_gemma":[0.9999136,0.00001011292,0.00002650159,0.00001313774,0.00001948397,0.00001724315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000539493,0.00004673672,0.0002580288,0.00003138213,0.000007831217,0.00001977857,0.000006623235,0.0000864664,0.9968714,0.00004383291,0.00004087548,0.002533034],"study_design_scores_gemma":[0.00002816205,0.002651761,0.00648833,0.000009680291,0.00002941935,0.0004941696,0.00001487024,0.00081875,0.985623,0.00006938599,0.003767967,0.000004494941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903378,0.001318261,0.006001557,0.0001010458,0.0000419701,0.00007037623,0.0001637783,0.0001129302,0.001852242],"genre_scores_gemma":[0.9945813,0.0005100515,0.002530719,0.00008300737,0.00001518266,0.00002171945,0.0005127035,0.00001623912,0.001729176],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009057257,"threshold_uncertainty_score":0.003029943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04695443840884956,"score_gpt":0.3340130578252408,"score_spread":0.2870586194163912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}