{"id":"W4408307938","doi":"10.1002/ped4.12472","title":"Retinoma: An overview","year":2025,"lang":"en","type":"review","venue":"Pediatric Investigation","topic":"Ocular Oncology and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Clinical Evaluative Sciences; Centre for Global Health Research; Hospital for Sick Children; Public Health Ontario; University of Toronto","funders":"","keywords":"Retinoblastoma; Malignant transformation; Carcinogenesis; Cancer research; Epigenetics; Biology; Retinal; Senescence; Microsatellite instability; Downregulation and upregulation; Pathology; Cancer; Gene; Bioinformatics; Medicine; Genetics; Ophthalmology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002270366,0.0003019771,0.001123538,0.0003430491,0.00008544178,0.00001328913,0.00009822768,0.0005486012,0.00007622467],"category_scores_gemma":[0.0001941176,0.0002427957,0.000294074,0.0006912545,0.00004424656,0.00008138861,0.00003898118,0.000343421,0.0002968666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001885609,"about_ca_system_score_gemma":0.001452706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001092637,"about_ca_topic_score_gemma":0.000001844567,"domain_scores_codex":[0.9985087,0.0002431424,0.0004691567,0.0004119267,0.0001770161,0.0001900618],"domain_scores_gemma":[0.9989128,0.0001299994,0.000283322,0.0004280384,0.00007162796,0.0001742858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004732874,0.0001378021,0.003533782,0.06859703,0.0001423503,0.0001010634,0.0000331324,4.419655e-8,2.037542e-8,0.00099202,0.002344448,0.9241136],"study_design_scores_gemma":[0.000536882,0.0002486953,0.0006115753,0.004949053,0.01382913,0.00007403357,0.00000247685,0.000002482423,4.934085e-7,0.000716192,0.9787712,0.0002577835],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007930029,0.9964314,0.000003561806,0.00006507751,0.0003839897,0.001021624,0.00002157723,0.0001011456,0.001892313],"genre_scores_gemma":[0.000004865144,0.9943663,0.0008712839,0.0002255405,0.0008649876,0.0001569126,0.00177271,0.00002762562,0.001709773],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9764267,"threshold_uncertainty_score":0.9900923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1078821592718325,"score_gpt":0.3986082583690413,"score_spread":0.2907260990972088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}