{"id":"W4408326250","doi":"10.1158/1538-7445.genfunc25-ia026","title":"Abstract IA026: Pan-cancer <i>N</i>-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as a therapeutic target for head and neck cancers","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Head and neck; Medicine; Head and neck cancer; Cancer; Brain cancer; Atlas (anatomy); Oncology; Internal medicine; Surgery; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002279511,0.0003895156,0.0003079943,0.000474902,0.0002274911,0.0005399997,0.0002109591,0.0002950426,0.002768293],"category_scores_gemma":[0.0001123422,0.0001607778,0.0002740439,0.0003647861,0.000154674,0.0002369393,0.0003303671,0.0005814226,0.0007988506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003916141,"about_ca_system_score_gemma":0.0003246871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001375673,"about_ca_topic_score_gemma":0.002234418,"domain_scores_codex":[0.9998827,0.00001159176,0.000006497625,0.00002424534,0.00005180075,0.00002300539],"domain_scores_gemma":[0.9999504,0.000004580453,0.000009160874,0.000007968691,0.00001423945,0.00001370923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002630336,0.00002596395,0.002276511,0.00004057123,0.00001662612,0.0001053138,0.00001680383,0.0003046521,0.9893986,0.0001846958,0.001983071,0.005384268],"study_design_scores_gemma":[0.00003533369,0.0004580553,0.05667973,0.00001688647,0.00006238746,0.002221272,0.0001077643,0.007202508,0.9016687,0.0003607152,0.03116252,0.00002403907],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9499075,0.002498998,0.01765973,0.0008937176,0.0001471025,0.0001572788,0.01571373,0.001251034,0.01177081],"genre_scores_gemma":[0.9361109,0.002550574,0.0258668,0.0005999058,0.00004436819,0.0001326649,0.02148687,0.0002550468,0.0129528],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002768293,"threshold_uncertainty_score":0.009260893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03458043876608569,"score_gpt":0.380027069831626,"score_spread":0.3454466310655404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}