{"id":"W4408337415","doi":"10.1002/ajh.27655","title":"<scp><i>TP53</i></scp>‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management","year":2025,"lang":"en","type":"review","venue":"American Journal of Hematology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Astellas Pharma; Celgene; AbbVie Canada; Kura Oncology","keywords":"Myeloid leukemia; Medicine; Venetoclax; Cancer; Oncology; Myelodysplastic syndromes; Internal medicine; Myeloid; Population; Bioinformatics; Cancer research; Immunology; Leukemia; Biology; Bone marrow","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00139824,0.0006738452,0.001227036,0.002579662,0.0002060921,0.0009142064,0.0009648725,0.0009711079,0.003525014],"category_scores_gemma":[0.002910344,0.000287243,0.0007498869,0.001415632,0.0003135638,0.001334595,0.0006218502,0.002374899,0.002610735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008789904,"about_ca_system_score_gemma":0.001181431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001759653,"about_ca_topic_score_gemma":0.004239866,"domain_scores_codex":[0.9996564,0.00008999699,0.00006772248,0.00003361149,0.0001249282,0.00002740268],"domain_scores_gemma":[0.9982508,0.0006833284,0.0001997717,0.00003224985,0.0006996435,0.0001341498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009300916,0.00003897812,0.0007435196,0.004730937,0.0001212197,0.0002564316,0.0000424119,0.0003547061,0.0007840975,0.001048513,0.1302718,0.8615144],"study_design_scores_gemma":[0.00003818108,0.0001351301,0.001898786,0.009365669,0.0003690203,0.002360988,0.00004828432,0.0003257369,0.0003286821,0.001125443,0.983977,0.00002697802],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004568001,0.9885895,0.001130495,0.004666758,0.00182596,0.00002164096,0.000229069,0.00008331508,0.00299648],"genre_scores_gemma":[0.002343067,0.9872988,0.002032568,0.002967445,0.003142053,0.00002897196,0.0006850054,0.00001875887,0.001483436],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003525014,"threshold_uncertainty_score":0.01179236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01547931291521099,"score_gpt":0.3319085732240816,"score_spread":0.3164292603088706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}