{"id":"W4408345274","doi":"10.1159/000544989","title":"Targeted Rapid Endotoxin Adsorption (TREA): can we bring precision medicine to sepsis?","year":2025,"lang":"en","type":"review","venue":"Blood Purification","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Tornado Spectral Systems (Canada)","funders":"","keywords":"Hemofiltration; Sepsis; Septic shock; Medicine; Intensive care medicine; Extracorporeal; Immunology; Hemodialysis; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008176328,0.0005360867,0.001371505,0.00107587,0.0001936237,0.00003112197,0.0005111795,0.0008901011,0.000620953],"category_scores_gemma":[0.0007238214,0.0004528351,0.0003191083,0.000855711,0.00007356946,0.0001202111,0.0001005766,0.0005239761,0.001261234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001496524,"about_ca_system_score_gemma":0.0003935744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008588564,"about_ca_topic_score_gemma":0.0000122354,"domain_scores_codex":[0.9963889,0.001082234,0.001264576,0.0007320742,0.0001069866,0.0004252288],"domain_scores_gemma":[0.9976357,0.0005495696,0.0006648451,0.000927275,0.0001774547,0.0000451366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006028346,0.0000919663,7.481918e-7,0.002897801,0.0003348904,0.000001606863,0.000277123,8.900266e-7,0.03202744,0.0002304723,0.004902742,0.959174],"study_design_scores_gemma":[0.0007098092,0.0001671085,0.00003954574,0.01410927,0.001385935,0.00004725575,0.00004048184,6.246881e-7,0.02449133,0.00004426416,0.958582,0.0003823262],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009947551,0.993834,0.0003595149,0.0008743673,0.001143229,0.002352236,0.00005857776,0.0001892694,0.001089363],"genre_scores_gemma":[0.0002943731,0.9838088,0.0001303097,0.00006586766,0.0001701486,0.0005368991,0.00435032,0.00004626039,0.01059698],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9587917,"threshold_uncertainty_score":0.9997923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02620430932972118,"score_gpt":0.2969591398286553,"score_spread":0.2707548304989341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}