{"id":"W4408360262","doi":"10.1016/j.bbih.2025.100977","title":"Protocol for project MHISS: Mental Health and Immunodynamics of Social Stress","year":2025,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"National Institute of Mental Health","keywords":"Mental health; Protocol (science); Psychology; Stress (linguistics); Mental stress; Applied psychology; Sociology; Medicine; Psychiatry; Alternative medicine; Philosophy; Linguistics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002702124,0.0002258215,0.0004543311,0.0002230132,0.001087963,0.00005797558,0.000370056,0.00009160167,0.00001128871],"category_scores_gemma":[0.0002466314,0.0002239248,0.0001178401,0.0003953103,0.000253211,0.0001144869,0.0002071562,0.0003010812,4.891131e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002443087,"about_ca_system_score_gemma":0.001754189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002087008,"about_ca_topic_score_gemma":0.0002736493,"domain_scores_codex":[0.9974688,0.0006815981,0.0006763468,0.0003732104,0.0002528568,0.0005471754],"domain_scores_gemma":[0.9987158,0.0003062165,0.0004478137,0.0003709271,0.0000564502,0.0001028349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.007381233,0.005976101,0.01098714,0.006717735,0.00004112188,0.000007385437,0.02280337,0.00000175928,0.08521893,0.01744124,0.01426375,0.8291602],"study_design_scores_gemma":[0.04152322,0.02063992,0.4971856,0.004351861,0.00009518183,0.0001447846,0.03626018,0.001921991,0.06138308,0.0007915297,0.3329166,0.002786032],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.7030644,0.0001729041,0.0002925321,0.008564138,0.000287077,0.2853693,0.001832791,0.0001710667,0.0002458064],"genre_scores_gemma":[0.4000888,0.0004435293,0.001716593,0.01123097,0.00010798,0.5813619,0.0003045727,0.0001685773,0.004577161],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8263742,"threshold_uncertainty_score":0.9131388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07822662054374857,"score_gpt":0.4442150268948808,"score_spread":0.3659884063511322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}